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The Complex Mechanisms by Which Neurons Die Following DNA Damage in Neurodegenerative Diseases

Human cells are exposed to numerous exogenous and endogenous insults every day. Unlike other molecules, DNA cannot be replaced by resynthesis, hence damage to DNA can have major consequences for the cell. The DNA damage response contains overlapping signalling networks that repair DNA and hence main...

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Detalles Bibliográficos
Autores principales: Shadfar, Sina, Brocardo, Mariana, Atkin, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910227/
https://www.ncbi.nlm.nih.gov/pubmed/35269632
http://dx.doi.org/10.3390/ijms23052484