Cargando…

Investigation of the Molecular Details of the Interactions of Selenoglycosides and Human Galectin-3

Human galectin-3 (hGal-3) is involved in a variety of biological processes and is implicated in wide range of diseases. As a result, targeting hGal-3 for clinical applications has become an intense area of research. As a step towards the development of novel hGal-3 inhibitors, we describe a study of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raics, Mária, Balogh, Álex Kálmán, Kishor, Chandan, Timári, István, Medrano, Francisco J., Romero, Antonio, Go, Rob Marc, Blanchard, Helen, Szilágyi, László, E. Kövér, Katalin, Fehér, Krisztina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910297/ https://www.ncbi.nlm.nih.gov/pubmed/35269646 http://dx.doi.org/10.3390/ijms23052494

Ejemplares similares

(77)Se-Enriched Selenoglycoside Enables Significant Enhancement in NMR Spectroscopic Monitoring of Glycan–Protein Interactions
por: Timári, István, et al.
Publicado: (2022)

Selenoglycosides as Lectin Ligands: (77)Se‐Edited CPMG‐HSQMBC NMR Spectroscopy To Monitor Biomedically Relevant Interactions
por: Raics, Mária, et al.
Publicado: (2019)

Exploring the Molecular Interactions of Symmetrical and Unsymmetrical Selenoglycosides with Human Galectin-1 and Galectin-3
por: Pirone, Luciano, et al.
Publicado: (2022)

Precise Measurement of Long-Range Heteronuclear Coupling Constants by a Novel Broadband Proton–Proton-Decoupled CPMG-HSQMBC Method
por: Timári, István, et al.
Publicado: (2015)

Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes
por: Franco, Jaime, et al.
Publicado: (2017)

Ultrahigh-Resolution Homo- and Heterodecoupled (1)H and TOCSY NMR Experiments
por: Timári, István, et al.
Publicado: (2022)

Probing pattern and dynamics of disulfide bridges using synthesis and NMR of an ion channel blocker peptide toxin with multiple diselenide bonds
por: Fehér, Krisztina, et al.
Publicado: (2016)

Phosphorylated Peptide Derived from the Myosin Phosphatase Target Subunit Is a Novel Inhibitor of Protein Phosphatase-1
por: Kónya, Zoltán, et al.
Publicado: (2023)

Photochemical and Structural Studies on Cyclic Peptide Models
por: Nagy, Tamás Milán, et al.
Publicado: (2018)

An engineered scorpion toxin analogue with improved Kv1.3 selectivity displays reduced conformational flexibility
por: Bartok, Adam, et al.
Publicado: (2015)

Detailed severity assessment of Cincinnati Prehospital Stroke Scale to detect large vessel occlusion in acute ischemic stroke
por: Tarkanyi, Gabor, et al.
Publicado: (2020)

Placental Protein 13 (PP13) – A Placental Immunoregulatory Galectin Protecting Pregnancy
por: Than, Nándor Gábor, et al.
Publicado: (2014)

Structural Characterization of Rat Galectin-5, an N-Tailed Monomeric Proto-Type-like Galectin
por: Ruiz, Federico M., et al.
Publicado: (2021)

Placental Galectins Are Key Players in Regulating the Maternal Adaptive Immune Response
por: Balogh, Andrea, et al.
Publicado: (2019)

Real-time pure shift (15)N HSQC of proteins: a real improvement in resolution and sensitivity
por: Kiraly, Peter, et al.
Publicado: (2015)

A case study on the potential angiogenic effect of human chorionic gonadotropin hormone in rapid progression and spontaneous regression of metastatic renal cell carcinoma during pregnancy and after surgical abortion
por: Mangel, László, et al.
Publicado: (2015)

Rapid Identification of Potential Drug Candidates from Multi-Million Compounds’ Repositories. Combination of 2D Similarity Search with 3D Ligand/Structure Based Methods and In Vitro Screening
por: Szilágyi, Katalin, et al.
Publicado: (2021)

Hemorheological Parameters in Diabetic Patients: Role of Glucose Lowering Therapies
por: Biro, Katalin, et al.
Publicado: (2021)

Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis
por: Gönczi, Mónika, et al.
Publicado: (2023)

Silica@zirconia Core@shell Nanoparticles for Nucleic Acid Building Block Sorption
por: Naszályi Nagy, Livia, et al.
Publicado: (2021)

Platelet Aggregometry Testing: Molecular Mechanisms, Techniques and Clinical Implications
por: Koltai, Katalin, et al.
Publicado: (2017)

Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail
por: Flores-Ibarra, Andrea, et al.
Publicado: (2018)

Influence of Galectin-9 Treatment on the Phenotype and Function of NK-92MI Cells in the Presence of Different Serum Supplements
por: Meggyes, Matyas, et al.
Publicado: (2021)

Placental galectins regulate innate and adaptive immune responses in pregnancy
por: Oravecz, Orsolya, et al.
Publicado: (2022)

High Prevalence of Non-Vaccinated Oncogenic Human Papillomavirus Genotypes in High-Grade Squamous Intraepithelial Lesions of the Cervix: Thought-Provoking Results of a Detailed HPV Genotype Analysis
por: Rideg, Orsolya, et al.
Publicado: (2022)

Functional characterization of the idtF and idtP genes in the Claviceps paspali indole diterpene biosynthetic gene cluster
por: Kozák, László, et al.
Publicado: (2020)

Hydrothermal Synthesis and Gas Sensing of Monoclinic MoO(3) Nanosheets
por: Nagyné-Kovács, Teodóra, et al.
Publicado: (2020)

Molecular Analysis of Cystic Fibrosis Patients in Hungary – An Update to the Mutational Spectrum
por: Ivády, Gergely, et al.
Publicado: (2015)

Preparation of neuroprotective condensed 1,4-benzoxazepines by regio- and diastereoselective domino Knoevenagel–[1,5]-hydride shift cyclization reaction
por: Tóth, László, et al.
Publicado: (2014)

Design and Selection of Novel C1s Inhibitors by In Silico and In Vitro Approaches
por: Szilágyi, Katalin, et al.
Publicado: (2019)

Inhibition of protein phosphatase-1 and -2A by ellagitannins: structure-inhibitory potency relationships and influences on cellular systems
por: Kónya, Zoltán, et al.
Publicado: (2019)

DMSO-Induced Unfolding of the Antifungal Disulfide Protein PAF and Its Inactive Variant: A Combined NMR and DSC Study
por: Czajlik, András, et al.
Publicado: (2023)

Genomic Epidemiology and Evolution of Fowl Adenovirus 1
por: Jakab, Szilvia, et al.
Publicado: (2023)

Helsmoortel–Van der Aa Syndrome—Cardiothoracic and Ectodermal Manifestations in Two Patients as Further Support of a Previous Observation on Phenotypic Overlap with RASopathies
por: Szabó, Tímea Margit, et al.
Publicado: (2022)

Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8
por: Bohari, Mohammad H., et al.
Publicado: (2016)

Effects of Functional Training on Sarcopenia in Elderly Women in the Presence or Absence of ACE Inhibitors
por: Mile, Marianna, et al.
Publicado: (2021)

Hungarian Fine-to-Coarse Aggregate, a Possible Constituent of Near-Vessel Structural Concrete of Nuclear Power Plants
por: Gméling, Katalin, et al.
Publicado: (2023)

Screening for Peripheral Artery Disease Using an Automated Four-Limb Blood Pressure Monitor Equipped with Toe–Brachial Index Measurement
por: Fendrik, Krisztina, et al.
Publicado: (2023)

Selectively Modified Lactose and N-Acetyllactosamine Analogs at Three Key Positions to Afford Effective Galectin-3 Ligands †
por: Abdullayev, Shuay, et al.
Publicado: (2023)

4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study
por: Madách, Krisztina, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_jvo3dgc97n5psdbph01huj8u8u