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A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application

Alpha-1 antitrypsin (AAT) is the canonical serine protease inhibitor of neutrophil-derived proteases and can modulate innate immune mechanisms through its anti-inflammatory activities mediated by a broad spectrum of protein, cytokine, and cell surface interactions. AAT contains a reactive methionine...

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Detalles Bibliográficos
Autores principales: O’Brien, Michael E., Murray, Grace, Gogoi, Debananda, Yusuf, Azeez, McCarthy, Cormac, Wormald, Mark R., Casey, Michelle, Gabillard-Lefort, Claudie, McElvaney, Noel G., Reeves, Emer P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910375/
https://www.ncbi.nlm.nih.gov/pubmed/35269582
http://dx.doi.org/10.3390/ijms23052441