Amelioration of Endotoxin-Induced Acute Lung Injury and Alveolar Epithelial Cells Apoptosis by Simvastatin Is Associated with Up-Regulation of Survivin/NF-kB/p65 Pathway

Disruption of the alveolar–endothelial barrier caused by inflammation leads to the progression of septic acute lung injury (ALI). In the present study, we investigated the beneficial effects of simvastatin on the endotoxin lipopolysaccharide (LPS)-induced ALI and its related mechanisms. A model of A...

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Detalles Bibliográficos
Autores principales: Nežić, Lana, Amidžić, Ljiljana, Škrbić, Ranko, Gajanin, Radoslav, Mandić, Danijela, Dumanović, Jelena, Milovanović, Zoran, Jaćević, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910433/
https://www.ncbi.nlm.nih.gov/pubmed/35269738
http://dx.doi.org/10.3390/ijms23052596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910433/
https://www.ncbi.nlm.nih.gov/pubmed/35269738
http://dx.doi.org/10.3390/ijms23052596

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