A Redox-Silent Analogue of Tocotrienol May Break the Homeostasis of Proteasomes in Human Malignant Mesothelioma Cells by Inhibiting STAT3 and NRF1

6-O-Carboxypropyl-alpha-tocotrienol (α-T3E) is a multi-target redox-silent analogue of tocotrienol that exhibits cytotoxicity against many cancer cells, including malignant mesothelioma (MM) cells. α-T3E has several molecular targets to effectively induce cytotoxicity against MM cells; however, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishii, Kyota, Fusegi, Momoka, Mori, Tatsuki, Teshima, Kosuke, Ninomiya, Nanako, Kohno, Kakeru, Sato, Ayami, Ishida, Tatsuya, Miyakoshi, Yuichi, Yano, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910454/
https://www.ncbi.nlm.nih.gov/pubmed/35269802
http://dx.doi.org/10.3390/ijms23052655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910454/
https://www.ncbi.nlm.nih.gov/pubmed/35269802
http://dx.doi.org/10.3390/ijms23052655

Ejemplares similares