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Better Agreement of Human Transcriptomic and Proteomic Cancer Expression Data at the Molecular Pathway Activation Level

Previously, we have shown that the aggregation of RNA-level gene expression profiles into quantitative molecular pathway activation metrics results in lesser batch effects and better agreement between different experimental platforms. Here, we investigate whether pathway level of data analysis provi...

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Detalles Bibliográficos
Autores principales: Raevskiy, Mikhail, Sorokin, Maxim, Zakharova, Galina, Tkachev, Victor, Borisov, Nicolas, Kuzmin, Denis, Kremenchutckaya, Kristina, Gudkov, Alexander, Kamashev, Dmitry, Buzdin, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910457/
https://www.ncbi.nlm.nih.gov/pubmed/35269755
http://dx.doi.org/10.3390/ijms23052611