Sirtuin 7 Deficiency Reduces Inflammation and Tubular Damage Induced by an Episode of Acute Kidney Injury

Acute kidney injury (AKI) is a public health problem worldwide. Sirtuins are a family of seven NAD+-dependent deacylases, Overexpression of Sirtuin 1, 3, and 5 protect against AKI. However, the role of Sirtuin 7 (Sirt7) in AKI is not known. Here, we analyzed how Sirt7 deficient mice (KO-Sirt7) were...

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Detalles Bibliográficos
Autores principales: Sánchez-Navarro, Andrea, Martínez-Rojas, Miguel Ángel, Albarrán-Godinez, Adrián, Pérez-Villalva, Rosalba, Auwerx, Johan, de la Cruz, Abigail, Noriega, Lilia G., Rosetti, Florencia, Bobadilla, Norma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910458/
https://www.ncbi.nlm.nih.gov/pubmed/35269715
http://dx.doi.org/10.3390/ijms23052573

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