Doxycycline Decreases Atherosclerotic Lesions in the Aorta of ApoE(-⁄-) and Ovariectomized Mice with Correlation to Reduced MMP-2 Activity

Atherogenic events promote changes in vessel walls, with alteration of the redox state, and increased activity of matrix metalloproteinases (MMPs). Thus, this study aims to evaluate aortic remodeling, MMP activity, and reactive oxygen species (ROS) levels after treatment with doxycycline in ApoE(-⁄-...

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Detalles Bibliográficos
Autores principales: Rodrigues, Keuri E., Azevedo, Aline, Gonçalves, Pricila R., Pontes, Maria H. B., Alves, Gustavo M., Oliveira, Ruan R., Amarante, Cristine B., Issa, João P. M., Gerlach, Raquel F., Prado, Alejandro F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910467/
https://www.ncbi.nlm.nih.gov/pubmed/35269673
http://dx.doi.org/10.3390/ijms23052532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910467/
https://www.ncbi.nlm.nih.gov/pubmed/35269673
http://dx.doi.org/10.3390/ijms23052532

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