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Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach

The elderly, especially those individuals with pre-existing health problems, have been disproportionally at a higher risk during the COVID-19 pandemic. Residents of long-term care facilities have been gravely affected by the pandemic and resident death numbers have been far above those of the genera...

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Autores principales: Asgary, Ali, Blue, Hudson, Solis, Adriano O., McCarthy, Zachary, Najafabadi, Mahdi, Tofighi, Mohammad Ali, Wu, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910468/
https://www.ncbi.nlm.nih.gov/pubmed/35270344
http://dx.doi.org/10.3390/ijerph19052635
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author Asgary, Ali
Blue, Hudson
Solis, Adriano O.
McCarthy, Zachary
Najafabadi, Mahdi
Tofighi, Mohammad Ali
Wu, Jianhong
author_facet Asgary, Ali
Blue, Hudson
Solis, Adriano O.
McCarthy, Zachary
Najafabadi, Mahdi
Tofighi, Mohammad Ali
Wu, Jianhong
author_sort Asgary, Ali
collection PubMed
description The elderly, especially those individuals with pre-existing health problems, have been disproportionally at a higher risk during the COVID-19 pandemic. Residents of long-term care facilities have been gravely affected by the pandemic and resident death numbers have been far above those of the general population. To better understand how infectious diseases such as COVID-19 can spread through long-term care facilities, we developed an agent-based simulation tool that uses a contact matrix adapted from previous infection control research in these types of facilities. This matrix accounts for the average distinct daily contacts between seven different agent types that represent the roles of individuals in long-term care facilities. The simulation results were compared to actual COVID-19 outbreaks in some of the long-term care facilities in Ontario, Canada. Our analysis shows that this simulation tool is capable of predicting the number of resident deaths after 50 days with a less than 0.1 variation in death rate. We modeled and predicted the effectiveness of infection control measures by utilizing this simulation tool. We found that to reduce the number of resident deaths, the effectiveness of personal protective equipment must be above 50%. We also found that daily random COVID-19 tests for as low as less than 10% of a long-term care facility’s population will reduce the number of resident deaths by over 75%. The results further show that combining several infection control measures will lead to more effective outcomes.
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spelling pubmed-89104682022-03-11 Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach Asgary, Ali Blue, Hudson Solis, Adriano O. McCarthy, Zachary Najafabadi, Mahdi Tofighi, Mohammad Ali Wu, Jianhong Int J Environ Res Public Health Article The elderly, especially those individuals with pre-existing health problems, have been disproportionally at a higher risk during the COVID-19 pandemic. Residents of long-term care facilities have been gravely affected by the pandemic and resident death numbers have been far above those of the general population. To better understand how infectious diseases such as COVID-19 can spread through long-term care facilities, we developed an agent-based simulation tool that uses a contact matrix adapted from previous infection control research in these types of facilities. This matrix accounts for the average distinct daily contacts between seven different agent types that represent the roles of individuals in long-term care facilities. The simulation results were compared to actual COVID-19 outbreaks in some of the long-term care facilities in Ontario, Canada. Our analysis shows that this simulation tool is capable of predicting the number of resident deaths after 50 days with a less than 0.1 variation in death rate. We modeled and predicted the effectiveness of infection control measures by utilizing this simulation tool. We found that to reduce the number of resident deaths, the effectiveness of personal protective equipment must be above 50%. We also found that daily random COVID-19 tests for as low as less than 10% of a long-term care facility’s population will reduce the number of resident deaths by over 75%. The results further show that combining several infection control measures will lead to more effective outcomes. MDPI 2022-02-24 /pmc/articles/PMC8910468/ /pubmed/35270344 http://dx.doi.org/10.3390/ijerph19052635 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Asgary, Ali
Blue, Hudson
Solis, Adriano O.
McCarthy, Zachary
Najafabadi, Mahdi
Tofighi, Mohammad Ali
Wu, Jianhong
Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach
title Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach
title_full Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach
title_fullStr Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach
title_full_unstemmed Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach
title_short Modeling COVID-19 Outbreaks in Long-Term Care Facilities Using an Agent-Based Modeling and Simulation Approach
title_sort modeling covid-19 outbreaks in long-term care facilities using an agent-based modeling and simulation approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910468/
https://www.ncbi.nlm.nih.gov/pubmed/35270344
http://dx.doi.org/10.3390/ijerph19052635
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