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Modulatory Effects of Fractalkine on Inflammatory Response and Iron Metabolism of Lipopolysaccharide and Lipoteichoic Acid-Activated THP-1 Macrophages

Fractalkine (CX3CL1) acts as a chemokine as well as a regulator of iron metabolism. Fractalkine binds CX3CR1, the fractalkine receptor on the surface of monocytes/macrophages regulating different intracellular signalling pathways such as mitogen-activated protein kinase (MAPK), phospholipase C (PLC)...

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Detalles Bibliográficos
Autores principales: Pandur, Edina, Tamási, Kitti, Pap, Ramóna, Jánosa, Gergely, Sipos, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910483/
https://www.ncbi.nlm.nih.gov/pubmed/35269771
http://dx.doi.org/10.3390/ijms23052629