Zinc Prevents DNA Damage in Normal Cells but Shows Genotoxic and Cytotoxic Effects in Acute Myeloid Leukemia Cells

Genomic instability is prevented by the DNA damage response (DDR). Micronutrients, like zinc (Zn), are cofactors of DDR proteins, and micronutrient deficiencies have been related to increased cancer risk. Acute myeloid leukemia (AML) patients commonly present Zn deficiency. Moreover, reports point t...

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Detalles Bibliográficos
Autores principales: Costa, Maria Inês, Lapa, Beatriz Santos, Jorge, Joana, Alves, Raquel, Carreira, Isabel Marques, Sarmento-Ribeiro, Ana Bela, Gonçalves, Ana Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910549/
https://www.ncbi.nlm.nih.gov/pubmed/35269710
http://dx.doi.org/10.3390/ijms23052567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910549/
https://www.ncbi.nlm.nih.gov/pubmed/35269710
http://dx.doi.org/10.3390/ijms23052567

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