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Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles

Breastfeeding may protect women’s long-term cardiovascular health; however, breastfeeding-related postpartum lipid changes remain unclear. We aim to examine associations of breastfeeding duration with maternal lipids at 12 months postpartum. In a subsample (n = 79) of the Maternal and Developmental...

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Autores principales: Niu, Zhongzheng, Naya, Christine H., Reynaga, Lorena, Toledo-Corral, Claudia M., Johnson, Mark, Yang, Tingyu, Grubbs, Brendan, Lurvey, Nathana, Lerner, Deborah, Dunton, Genevieve F., Habre, Rima, Breton, Carrie V., Bastain, Theresa M., Farzan, Shohreh F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910591/
https://www.ncbi.nlm.nih.gov/pubmed/35270701
http://dx.doi.org/10.3390/ijerph19053008
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author Niu, Zhongzheng
Naya, Christine H.
Reynaga, Lorena
Toledo-Corral, Claudia M.
Johnson, Mark
Yang, Tingyu
Grubbs, Brendan
Lurvey, Nathana
Lerner, Deborah
Dunton, Genevieve F.
Habre, Rima
Breton, Carrie V.
Bastain, Theresa M.
Farzan, Shohreh F.
author_facet Niu, Zhongzheng
Naya, Christine H.
Reynaga, Lorena
Toledo-Corral, Claudia M.
Johnson, Mark
Yang, Tingyu
Grubbs, Brendan
Lurvey, Nathana
Lerner, Deborah
Dunton, Genevieve F.
Habre, Rima
Breton, Carrie V.
Bastain, Theresa M.
Farzan, Shohreh F.
author_sort Niu, Zhongzheng
collection PubMed
description Breastfeeding may protect women’s long-term cardiovascular health; however, breastfeeding-related postpartum lipid changes remain unclear. We aim to examine associations of breastfeeding duration with maternal lipids at 12 months postpartum. In a subsample (n = 79) of the Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) cohort, breastfeeding status and duration at 3, 6, and 12 months postpartum were self-reported. Serum levels of lipids, including total cholesterol, triglycerides (TG), high-, low-, and very low-density lipoprotein cholesterol (HDL-C, LDL-C, VLDL-C), were measured from blood samples collected at 12 months postpartum. We used linear regression models to compare lipids by breastfeeding duration, adjusting for potential confounders. Women who were breastfeeding at 12 months had higher HDL-C (mean: 41.74 mg/dL, 95% CI: 37.27–46.74 vs. 35.11 mg/dL, 95% CI: 31.42–39.24), lower TG (80.45 mg/dL, 95% CI: 66.20–97.77 vs. 119.11 mg/dL, 95% CI: 98.36–144.25), and lower VLDL-C (16.31 mg/dL, 95% CI: 13.23, 20.12 vs. 23.09 mg/dL, 95% CI: 18.61–28.65) compared to women who breastfed for <6 months. No lipids were significantly different between women who breastfed for 6–11 months and for <6 months. Each month’s increase in breastfeeding duration was significantly, inversely associated with TG and VLDL-C and positively with HDL-C. Adjusting for fasting status, demographics, pre-pregnancy body mass index, breastfeeding frequency, and pregnancy complications did not appreciably change effect estimates. Breastfeeding at 12 months postpartum and a longer duration of breastfeeding in the first year postpartum were both associated with increased HDL-C and decreased TG and VLDL-C at 12 months postpartum.
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spelling pubmed-89105912022-03-11 Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles Niu, Zhongzheng Naya, Christine H. Reynaga, Lorena Toledo-Corral, Claudia M. Johnson, Mark Yang, Tingyu Grubbs, Brendan Lurvey, Nathana Lerner, Deborah Dunton, Genevieve F. Habre, Rima Breton, Carrie V. Bastain, Theresa M. Farzan, Shohreh F. Int J Environ Res Public Health Article Breastfeeding may protect women’s long-term cardiovascular health; however, breastfeeding-related postpartum lipid changes remain unclear. We aim to examine associations of breastfeeding duration with maternal lipids at 12 months postpartum. In a subsample (n = 79) of the Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) cohort, breastfeeding status and duration at 3, 6, and 12 months postpartum were self-reported. Serum levels of lipids, including total cholesterol, triglycerides (TG), high-, low-, and very low-density lipoprotein cholesterol (HDL-C, LDL-C, VLDL-C), were measured from blood samples collected at 12 months postpartum. We used linear regression models to compare lipids by breastfeeding duration, adjusting for potential confounders. Women who were breastfeeding at 12 months had higher HDL-C (mean: 41.74 mg/dL, 95% CI: 37.27–46.74 vs. 35.11 mg/dL, 95% CI: 31.42–39.24), lower TG (80.45 mg/dL, 95% CI: 66.20–97.77 vs. 119.11 mg/dL, 95% CI: 98.36–144.25), and lower VLDL-C (16.31 mg/dL, 95% CI: 13.23, 20.12 vs. 23.09 mg/dL, 95% CI: 18.61–28.65) compared to women who breastfed for <6 months. No lipids were significantly different between women who breastfed for 6–11 months and for <6 months. Each month’s increase in breastfeeding duration was significantly, inversely associated with TG and VLDL-C and positively with HDL-C. Adjusting for fasting status, demographics, pre-pregnancy body mass index, breastfeeding frequency, and pregnancy complications did not appreciably change effect estimates. Breastfeeding at 12 months postpartum and a longer duration of breastfeeding in the first year postpartum were both associated with increased HDL-C and decreased TG and VLDL-C at 12 months postpartum. MDPI 2022-03-04 /pmc/articles/PMC8910591/ /pubmed/35270701 http://dx.doi.org/10.3390/ijerph19053008 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Niu, Zhongzheng
Naya, Christine H.
Reynaga, Lorena
Toledo-Corral, Claudia M.
Johnson, Mark
Yang, Tingyu
Grubbs, Brendan
Lurvey, Nathana
Lerner, Deborah
Dunton, Genevieve F.
Habre, Rima
Breton, Carrie V.
Bastain, Theresa M.
Farzan, Shohreh F.
Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles
title Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles
title_full Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles
title_fullStr Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles
title_full_unstemmed Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles
title_short Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles
title_sort association of breastfeeding duration with 12-month postpartum blood lipids in a predominately lower-income hispanic pregnancy cohort in los angeles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910591/
https://www.ncbi.nlm.nih.gov/pubmed/35270701
http://dx.doi.org/10.3390/ijerph19053008
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