Cargando…
Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles
Breastfeeding may protect women’s long-term cardiovascular health; however, breastfeeding-related postpartum lipid changes remain unclear. We aim to examine associations of breastfeeding duration with maternal lipids at 12 months postpartum. In a subsample (n = 79) of the Maternal and Developmental...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910591/ https://www.ncbi.nlm.nih.gov/pubmed/35270701 http://dx.doi.org/10.3390/ijerph19053008 |
_version_ | 1784666527540183040 |
---|---|
author | Niu, Zhongzheng Naya, Christine H. Reynaga, Lorena Toledo-Corral, Claudia M. Johnson, Mark Yang, Tingyu Grubbs, Brendan Lurvey, Nathana Lerner, Deborah Dunton, Genevieve F. Habre, Rima Breton, Carrie V. Bastain, Theresa M. Farzan, Shohreh F. |
author_facet | Niu, Zhongzheng Naya, Christine H. Reynaga, Lorena Toledo-Corral, Claudia M. Johnson, Mark Yang, Tingyu Grubbs, Brendan Lurvey, Nathana Lerner, Deborah Dunton, Genevieve F. Habre, Rima Breton, Carrie V. Bastain, Theresa M. Farzan, Shohreh F. |
author_sort | Niu, Zhongzheng |
collection | PubMed |
description | Breastfeeding may protect women’s long-term cardiovascular health; however, breastfeeding-related postpartum lipid changes remain unclear. We aim to examine associations of breastfeeding duration with maternal lipids at 12 months postpartum. In a subsample (n = 79) of the Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) cohort, breastfeeding status and duration at 3, 6, and 12 months postpartum were self-reported. Serum levels of lipids, including total cholesterol, triglycerides (TG), high-, low-, and very low-density lipoprotein cholesterol (HDL-C, LDL-C, VLDL-C), were measured from blood samples collected at 12 months postpartum. We used linear regression models to compare lipids by breastfeeding duration, adjusting for potential confounders. Women who were breastfeeding at 12 months had higher HDL-C (mean: 41.74 mg/dL, 95% CI: 37.27–46.74 vs. 35.11 mg/dL, 95% CI: 31.42–39.24), lower TG (80.45 mg/dL, 95% CI: 66.20–97.77 vs. 119.11 mg/dL, 95% CI: 98.36–144.25), and lower VLDL-C (16.31 mg/dL, 95% CI: 13.23, 20.12 vs. 23.09 mg/dL, 95% CI: 18.61–28.65) compared to women who breastfed for <6 months. No lipids were significantly different between women who breastfed for 6–11 months and for <6 months. Each month’s increase in breastfeeding duration was significantly, inversely associated with TG and VLDL-C and positively with HDL-C. Adjusting for fasting status, demographics, pre-pregnancy body mass index, breastfeeding frequency, and pregnancy complications did not appreciably change effect estimates. Breastfeeding at 12 months postpartum and a longer duration of breastfeeding in the first year postpartum were both associated with increased HDL-C and decreased TG and VLDL-C at 12 months postpartum. |
format | Online Article Text |
id | pubmed-8910591 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89105912022-03-11 Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles Niu, Zhongzheng Naya, Christine H. Reynaga, Lorena Toledo-Corral, Claudia M. Johnson, Mark Yang, Tingyu Grubbs, Brendan Lurvey, Nathana Lerner, Deborah Dunton, Genevieve F. Habre, Rima Breton, Carrie V. Bastain, Theresa M. Farzan, Shohreh F. Int J Environ Res Public Health Article Breastfeeding may protect women’s long-term cardiovascular health; however, breastfeeding-related postpartum lipid changes remain unclear. We aim to examine associations of breastfeeding duration with maternal lipids at 12 months postpartum. In a subsample (n = 79) of the Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) cohort, breastfeeding status and duration at 3, 6, and 12 months postpartum were self-reported. Serum levels of lipids, including total cholesterol, triglycerides (TG), high-, low-, and very low-density lipoprotein cholesterol (HDL-C, LDL-C, VLDL-C), were measured from blood samples collected at 12 months postpartum. We used linear regression models to compare lipids by breastfeeding duration, adjusting for potential confounders. Women who were breastfeeding at 12 months had higher HDL-C (mean: 41.74 mg/dL, 95% CI: 37.27–46.74 vs. 35.11 mg/dL, 95% CI: 31.42–39.24), lower TG (80.45 mg/dL, 95% CI: 66.20–97.77 vs. 119.11 mg/dL, 95% CI: 98.36–144.25), and lower VLDL-C (16.31 mg/dL, 95% CI: 13.23, 20.12 vs. 23.09 mg/dL, 95% CI: 18.61–28.65) compared to women who breastfed for <6 months. No lipids were significantly different between women who breastfed for 6–11 months and for <6 months. Each month’s increase in breastfeeding duration was significantly, inversely associated with TG and VLDL-C and positively with HDL-C. Adjusting for fasting status, demographics, pre-pregnancy body mass index, breastfeeding frequency, and pregnancy complications did not appreciably change effect estimates. Breastfeeding at 12 months postpartum and a longer duration of breastfeeding in the first year postpartum were both associated with increased HDL-C and decreased TG and VLDL-C at 12 months postpartum. MDPI 2022-03-04 /pmc/articles/PMC8910591/ /pubmed/35270701 http://dx.doi.org/10.3390/ijerph19053008 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Niu, Zhongzheng Naya, Christine H. Reynaga, Lorena Toledo-Corral, Claudia M. Johnson, Mark Yang, Tingyu Grubbs, Brendan Lurvey, Nathana Lerner, Deborah Dunton, Genevieve F. Habre, Rima Breton, Carrie V. Bastain, Theresa M. Farzan, Shohreh F. Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles |
title | Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles |
title_full | Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles |
title_fullStr | Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles |
title_full_unstemmed | Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles |
title_short | Association of Breastfeeding Duration with 12-Month Postpartum Blood Lipids in a Predominately Lower-Income Hispanic Pregnancy Cohort in Los Angeles |
title_sort | association of breastfeeding duration with 12-month postpartum blood lipids in a predominately lower-income hispanic pregnancy cohort in los angeles |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910591/ https://www.ncbi.nlm.nih.gov/pubmed/35270701 http://dx.doi.org/10.3390/ijerph19053008 |
work_keys_str_mv | AT niuzhongzheng associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT nayachristineh associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT reynagalorena associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT toledocorralclaudiam associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT johnsonmark associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT yangtingyu associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT grubbsbrendan associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT lurveynathana associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT lernerdeborah associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT duntongenevievef associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT habrerima associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT bretoncarriev associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT bastaintheresam associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles AT farzanshohrehf associationofbreastfeedingdurationwith12monthpostpartumbloodlipidsinapredominatelylowerincomehispanicpregnancycohortinlosangeles |