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Antiviral Drugs in Influenza

Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appe...

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Autores principales: Świerczyńska, Magdalena, Mirowska-Guzel, Dagmara M., Pindelska, Edyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910682/
https://www.ncbi.nlm.nih.gov/pubmed/35270708
http://dx.doi.org/10.3390/ijerph19053018
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author Świerczyńska, Magdalena
Mirowska-Guzel, Dagmara M.
Pindelska, Edyta
author_facet Świerczyńska, Magdalena
Mirowska-Guzel, Dagmara M.
Pindelska, Edyta
author_sort Świerczyńska, Magdalena
collection PubMed
description Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appeared on the market. This is a promising step in the fight against the influenza virus. This article presents the possibilities of using all available antiviral drugs specific for influenza A and B. We compare all currently recommended anti-influenza medications, considering their mechanisms of action, administration, indications, target groups, effectiveness, and safety profiles. We demonstrate that baloxavir marboxil presents a similar safety and efficacy profile to those of drugs already used in the treatment of influenza. Further research on combination therapy is highly recommended and may have promising results.
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spelling pubmed-89106822022-03-11 Antiviral Drugs in Influenza Świerczyńska, Magdalena Mirowska-Guzel, Dagmara M. Pindelska, Edyta Int J Environ Res Public Health Review Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appeared on the market. This is a promising step in the fight against the influenza virus. This article presents the possibilities of using all available antiviral drugs specific for influenza A and B. We compare all currently recommended anti-influenza medications, considering their mechanisms of action, administration, indications, target groups, effectiveness, and safety profiles. We demonstrate that baloxavir marboxil presents a similar safety and efficacy profile to those of drugs already used in the treatment of influenza. Further research on combination therapy is highly recommended and may have promising results. MDPI 2022-03-04 /pmc/articles/PMC8910682/ /pubmed/35270708 http://dx.doi.org/10.3390/ijerph19053018 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Świerczyńska, Magdalena
Mirowska-Guzel, Dagmara M.
Pindelska, Edyta
Antiviral Drugs in Influenza
title Antiviral Drugs in Influenza
title_full Antiviral Drugs in Influenza
title_fullStr Antiviral Drugs in Influenza
title_full_unstemmed Antiviral Drugs in Influenza
title_short Antiviral Drugs in Influenza
title_sort antiviral drugs in influenza
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910682/
https://www.ncbi.nlm.nih.gov/pubmed/35270708
http://dx.doi.org/10.3390/ijerph19053018
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