Cargando…
Antiviral Drugs in Influenza
Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appe...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910682/ https://www.ncbi.nlm.nih.gov/pubmed/35270708 http://dx.doi.org/10.3390/ijerph19053018 |
_version_ | 1784666557311352832 |
---|---|
author | Świerczyńska, Magdalena Mirowska-Guzel, Dagmara M. Pindelska, Edyta |
author_facet | Świerczyńska, Magdalena Mirowska-Guzel, Dagmara M. Pindelska, Edyta |
author_sort | Świerczyńska, Magdalena |
collection | PubMed |
description | Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appeared on the market. This is a promising step in the fight against the influenza virus. This article presents the possibilities of using all available antiviral drugs specific for influenza A and B. We compare all currently recommended anti-influenza medications, considering their mechanisms of action, administration, indications, target groups, effectiveness, and safety profiles. We demonstrate that baloxavir marboxil presents a similar safety and efficacy profile to those of drugs already used in the treatment of influenza. Further research on combination therapy is highly recommended and may have promising results. |
format | Online Article Text |
id | pubmed-8910682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89106822022-03-11 Antiviral Drugs in Influenza Świerczyńska, Magdalena Mirowska-Guzel, Dagmara M. Pindelska, Edyta Int J Environ Res Public Health Review Flu is a serious health, medical, and economic problem, but no therapy is yet available that has satisfactory results and reduces the occurrence of these problems. Nearly 20 years after the registration of the previous therapy, baloxavir marboxil, a drug with a new mechanism of action, recently appeared on the market. This is a promising step in the fight against the influenza virus. This article presents the possibilities of using all available antiviral drugs specific for influenza A and B. We compare all currently recommended anti-influenza medications, considering their mechanisms of action, administration, indications, target groups, effectiveness, and safety profiles. We demonstrate that baloxavir marboxil presents a similar safety and efficacy profile to those of drugs already used in the treatment of influenza. Further research on combination therapy is highly recommended and may have promising results. MDPI 2022-03-04 /pmc/articles/PMC8910682/ /pubmed/35270708 http://dx.doi.org/10.3390/ijerph19053018 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Świerczyńska, Magdalena Mirowska-Guzel, Dagmara M. Pindelska, Edyta Antiviral Drugs in Influenza |
title | Antiviral Drugs in Influenza |
title_full | Antiviral Drugs in Influenza |
title_fullStr | Antiviral Drugs in Influenza |
title_full_unstemmed | Antiviral Drugs in Influenza |
title_short | Antiviral Drugs in Influenza |
title_sort | antiviral drugs in influenza |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910682/ https://www.ncbi.nlm.nih.gov/pubmed/35270708 http://dx.doi.org/10.3390/ijerph19053018 |
work_keys_str_mv | AT swierczynskamagdalena antiviraldrugsininfluenza AT mirowskaguzeldagmaram antiviraldrugsininfluenza AT pindelskaedyta antiviraldrugsininfluenza |