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Cyclin-Dependent Kinases (CDKs) and the Human Cytomegalovirus-Encoded CDK Ortholog pUL97 Represent Highly Attractive Targets for Synergistic Drug Combinations

Human cytomegalovirus (HCMV) is a pathogenic human herpesvirus associated with serious, potentially life-threatening symptoms in the immunocompromised or immunonaïve host. The limitations encountered by antiviral therapy options currently available include a narrow panel of accessible targets, the i...

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Detalles Bibliográficos
Autores principales: Wild, Markus, Hahn, Friedrich, Brückner, Nadine, Schütz, Martin, Wangen, Christina, Wagner, Sabrina, Sommerer, Mona, Strobl, Stefan, Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910733/
https://www.ncbi.nlm.nih.gov/pubmed/35269635
http://dx.doi.org/10.3390/ijms23052493