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Bortezomib-Induced Epigenetic Alterations in Nerve Cells: Focus on the Mechanisms Contributing to the Peripheral Neuropathy Development

Bortezomib-induced peripheral neuropathy (BiPN) occurs in approximately 40% of patients with multiple myeloma. The induction of severe neuropathy entails the dose reduction or complete elimination of bortezomib (BTZ). Interestingly, discontinuation of BTZ mostly results in a reduction or complete re...

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Detalles Bibliográficos
Autores principales: Łuczkowska, Karolina, Rogińska, Dorota, Kulig, Piotr, Bielikowicz, Anna, Baumert, Bartłomiej, Machaliński, Bogusław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910765/
https://www.ncbi.nlm.nih.gov/pubmed/35269574
http://dx.doi.org/10.3390/ijms23052431