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Dysregulation of Oxygen Sensing/Response Pathways in Pregnancies Complicated by Idiopathic Intrauterine Growth Restriction and Early-Onset Preeclampsia
Preeclampsia (PE) and intrauterine growth restriction (IUGR) are the leading causes of maternal and fetal morbidity/mortality. The central deficit in both conditions is impaired placentation due to poor trophoblast invasion, resulting in a hypoxic milieu in which oxidative stress contributes to the...
Autores principales: | McCracken, Sharon A., Seeho, Sean K. M., Carrodus, Tamara, Park, Jenny H., Woodland, Narelle, Gallery, Eileen D. M., Morris, Jonathan M., Ashton, Anthony W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910827/ https://www.ncbi.nlm.nih.gov/pubmed/35269911 http://dx.doi.org/10.3390/ijms23052772 |
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