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Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?

(1) Background: Nowadays, pregnancy can be achieved by in vitro fertilisation (IVF) or by intracytoplasmic sperm injection (ICSI) for many infertile couples. However, implantation failure still remains a significant problem and it can be stressful for both patients and doctors. One of the key player...

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Autores principales: Zikopoulos, Athanasios, Galani, Apostolia, Siristatidis, Charalampos, Georgiou, Ioannis, Mastora, Eirini, Paraskevaidi, Maria, Zikopoulos, Konstantinos, Kolibianakis, Efstratios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910946/
https://www.ncbi.nlm.nih.gov/pubmed/35268308
http://dx.doi.org/10.3390/jcm11051217
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author Zikopoulos, Athanasios
Galani, Apostolia
Siristatidis, Charalampos
Georgiou, Ioannis
Mastora, Eirini
Paraskevaidi, Maria
Zikopoulos, Konstantinos
Kolibianakis, Efstratios
author_facet Zikopoulos, Athanasios
Galani, Apostolia
Siristatidis, Charalampos
Georgiou, Ioannis
Mastora, Eirini
Paraskevaidi, Maria
Zikopoulos, Konstantinos
Kolibianakis, Efstratios
author_sort Zikopoulos, Athanasios
collection PubMed
description (1) Background: Nowadays, pregnancy can be achieved by in vitro fertilisation (IVF) or by intracytoplasmic sperm injection (ICSI) for many infertile couples. However, implantation failure still remains a significant problem and it can be stressful for both patients and doctors. One of the key players for pregnancy achievement is the uterine environment. Hysteroscopy is the most reliable method to evaluate the uterine cavity and to identify any intauterine pathology. The aim of this retrospective study was to compare live birth ranges in between women who after a first failed IVF/ICSI attempt underwent a hysteroscopy and those who were evaluated by a transvaginal scan. (2) The retrospective study took place at the Assisted Reproductive Unit of the University Hospital of Ioannina, Greece, from 2017 to 2020. It included 334 women with normal findings in a repeat ultrasound scan after a failed IVF/ICSI trial, 137 of whom underwent in turn diagnostic hysteroscopy before the next IVF/ICSI. (3) Results: Live birth rates were higher in the study group (58/137 vs. 52/197 p = 0.0025). Abnormal endometrial findings were identified in 30% of the patients of the study group. (4) Conclusions: The addition of hysteroscopy as an additional investigation to those patients with a first failed IVF/ICSI could improve the rates of live births. A properly conducted RCT could lead to a robust answer.
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spelling pubmed-89109462022-03-11 Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial? Zikopoulos, Athanasios Galani, Apostolia Siristatidis, Charalampos Georgiou, Ioannis Mastora, Eirini Paraskevaidi, Maria Zikopoulos, Konstantinos Kolibianakis, Efstratios J Clin Med Perspective (1) Background: Nowadays, pregnancy can be achieved by in vitro fertilisation (IVF) or by intracytoplasmic sperm injection (ICSI) for many infertile couples. However, implantation failure still remains a significant problem and it can be stressful for both patients and doctors. One of the key players for pregnancy achievement is the uterine environment. Hysteroscopy is the most reliable method to evaluate the uterine cavity and to identify any intauterine pathology. The aim of this retrospective study was to compare live birth ranges in between women who after a first failed IVF/ICSI attempt underwent a hysteroscopy and those who were evaluated by a transvaginal scan. (2) The retrospective study took place at the Assisted Reproductive Unit of the University Hospital of Ioannina, Greece, from 2017 to 2020. It included 334 women with normal findings in a repeat ultrasound scan after a failed IVF/ICSI trial, 137 of whom underwent in turn diagnostic hysteroscopy before the next IVF/ICSI. (3) Results: Live birth rates were higher in the study group (58/137 vs. 52/197 p = 0.0025). Abnormal endometrial findings were identified in 30% of the patients of the study group. (4) Conclusions: The addition of hysteroscopy as an additional investigation to those patients with a first failed IVF/ICSI could improve the rates of live births. A properly conducted RCT could lead to a robust answer. MDPI 2022-02-24 /pmc/articles/PMC8910946/ /pubmed/35268308 http://dx.doi.org/10.3390/jcm11051217 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Zikopoulos, Athanasios
Galani, Apostolia
Siristatidis, Charalampos
Georgiou, Ioannis
Mastora, Eirini
Paraskevaidi, Maria
Zikopoulos, Konstantinos
Kolibianakis, Efstratios
Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?
title Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?
title_full Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?
title_fullStr Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?
title_full_unstemmed Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?
title_short Is Hysteroscopy Prior to IVF Associated with an Increased Probability of Live Births in Patients with Normal Transvaginal Scan Findings after Their First Failed IVF Trial?
title_sort is hysteroscopy prior to ivf associated with an increased probability of live births in patients with normal transvaginal scan findings after their first failed ivf trial?
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910946/
https://www.ncbi.nlm.nih.gov/pubmed/35268308
http://dx.doi.org/10.3390/jcm11051217
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