Prodrug-Based Targeting Approach for Inflammatory Bowel Diseases Therapy: Mechanistic Study of Phospholipid-Linker-Cyclosporine PLA(2)-Mediated Activation

Therapeutics with activity specifically at the inflamed sites throughout the gastrointestinal tract (GIT) would be a major advance in our therapeutic approach to inflammatory bowel disease (IBD). We aimed to develop the prodrug approach that can allow such site-specific drug delivery. Currently, usi...

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Detalles Bibliográficos
Autores principales: Markovic, Milica, Abramov-Harpaz, Karina, Regev, Clil, Ben-Shabat, Shimon, Aponick, Aaron, Zimmermann, Ellen M., Miller, Yifat, Dahan, Arik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910962/
https://www.ncbi.nlm.nih.gov/pubmed/35269813
http://dx.doi.org/10.3390/ijms23052673

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