Methylmercury Induces Mitochondria- and Endoplasmic Reticulum Stress-Dependent Pancreatic β-Cell Apoptosis via an Oxidative Stress-Mediated JNK Signaling Pathway

Methylmercury (MeHg), a long-lasting organic pollutant, is known to induce cytotoxic effects in mammalian cells. Epidemiological studies have suggested that environmental exposure to MeHg is linked to the development of diabetes mellitus (DM). The exact molecular mechanism of MeHg-induced pancreatic...

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Detalles Bibliográficos
Autores principales: Yang, Ching-Yao, Liu, Shing-Hwa, Su, Chin-Chuan, Fang, Kai-Min, Yang, Tsung-Yuan, Liu, Jui-Ming, Chen, Ya-Wen, Chang, Kai-Chih, Chuang, Haw-Ling, Wu, Cheng-Tien, Lee, Kuan-I, Huang, Chun-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910963/
https://www.ncbi.nlm.nih.gov/pubmed/35270009
http://dx.doi.org/10.3390/ijms23052858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910963/
https://www.ncbi.nlm.nih.gov/pubmed/35270009
http://dx.doi.org/10.3390/ijms23052858

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