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Methylmercury Induces Mitochondria- and Endoplasmic Reticulum Stress-Dependent Pancreatic β-Cell Apoptosis via an Oxidative Stress-Mediated JNK Signaling Pathway
Methylmercury (MeHg), a long-lasting organic pollutant, is known to induce cytotoxic effects in mammalian cells. Epidemiological studies have suggested that environmental exposure to MeHg is linked to the development of diabetes mellitus (DM). The exact molecular mechanism of MeHg-induced pancreatic...
Autores principales: | Yang, Ching-Yao, Liu, Shing-Hwa, Su, Chin-Chuan, Fang, Kai-Min, Yang, Tsung-Yuan, Liu, Jui-Ming, Chen, Ya-Wen, Chang, Kai-Chih, Chuang, Haw-Ling, Wu, Cheng-Tien, Lee, Kuan-I, Huang, Chun-Fa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910963/ https://www.ncbi.nlm.nih.gov/pubmed/35270009 http://dx.doi.org/10.3390/ijms23052858 |
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