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Decreased Serum Levels of SIRT1 and SIRT3 Correlate with Severity of Skin and Lung Fibrosis and Peripheral Microvasculopathy in Systemic Sclerosis

Systemic sclerosis (SSc, scleroderma) is a severe autoimmune connective tissue disease characterized by widespread peripheral microvasculopathy, and progressive cutaneous and visceral fibrosis, leading to significant organ dysfunction. Sirtuins (SIRTs) are a family of NAD-dependent protein deacetyla...

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Detalles Bibliográficos
Autores principales:	Manetti, Mirko, Rosa, Irene, Fioretto, Bianca Saveria, Matucci-Cerinic, Marco, Romano, Eloisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910971/ https://www.ncbi.nlm.nih.gov/pubmed/35268452 http://dx.doi.org/10.3390/jcm11051362

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