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Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
In this work, a procedure for fabricating porous alumina with the use of a carbon sacrificial template has been tested in order to optimize the fabrication of porous structures mimicking the porosity and mechanical properties of the human cortical bone. Two different sources of sacrificial carbon we...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911001/ https://www.ncbi.nlm.nih.gov/pubmed/35268984 http://dx.doi.org/10.3390/ma15051754 |
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author | González-Sánchez, Manuela Rivero-Antúnez, Pedro Cano-Crespo, Rafael Morales-Flórez, Víctor |
author_facet | González-Sánchez, Manuela Rivero-Antúnez, Pedro Cano-Crespo, Rafael Morales-Flórez, Víctor |
author_sort | González-Sánchez, Manuela |
collection | PubMed |
description | In this work, a procedure for fabricating porous alumina with the use of a carbon sacrificial template has been tested in order to optimize the fabrication of porous structures mimicking the porosity and mechanical properties of the human cortical bone. Two different sources of sacrificial carbon were used and compared, and different sintering and calcination routes were considered. The porosity of the alumina structures studied by Hg porosimetry revealed that the amount of porosity and the size and shape of the pores are still below the required values, although some acicular pores were clearly observed by SEM. Moreover, measured mechanical properties (Young’s modulus) remained below that of the bone, suggesting the need for further consolidation treatments. In summary, these encouraging results drive the optimization of future fabrication routes. |
format | Online Article Text |
id | pubmed-8911001 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89110012022-03-11 Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration González-Sánchez, Manuela Rivero-Antúnez, Pedro Cano-Crespo, Rafael Morales-Flórez, Víctor Materials (Basel) Article In this work, a procedure for fabricating porous alumina with the use of a carbon sacrificial template has been tested in order to optimize the fabrication of porous structures mimicking the porosity and mechanical properties of the human cortical bone. Two different sources of sacrificial carbon were used and compared, and different sintering and calcination routes were considered. The porosity of the alumina structures studied by Hg porosimetry revealed that the amount of porosity and the size and shape of the pores are still below the required values, although some acicular pores were clearly observed by SEM. Moreover, measured mechanical properties (Young’s modulus) remained below that of the bone, suggesting the need for further consolidation treatments. In summary, these encouraging results drive the optimization of future fabrication routes. MDPI 2022-02-25 /pmc/articles/PMC8911001/ /pubmed/35268984 http://dx.doi.org/10.3390/ma15051754 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article González-Sánchez, Manuela Rivero-Antúnez, Pedro Cano-Crespo, Rafael Morales-Flórez, Víctor Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration |
title | Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration |
title_full | Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration |
title_fullStr | Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration |
title_full_unstemmed | Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration |
title_short | Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration |
title_sort | fabrication of porous alumina structures by sps and carbon sacrificial template for bone regeneration |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911001/ https://www.ncbi.nlm.nih.gov/pubmed/35268984 http://dx.doi.org/10.3390/ma15051754 |
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