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Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration

In this work, a procedure for fabricating porous alumina with the use of a carbon sacrificial template has been tested in order to optimize the fabrication of porous structures mimicking the porosity and mechanical properties of the human cortical bone. Two different sources of sacrificial carbon we...

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Autores principales: González-Sánchez, Manuela, Rivero-Antúnez, Pedro, Cano-Crespo, Rafael, Morales-Flórez, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911001/
https://www.ncbi.nlm.nih.gov/pubmed/35268984
http://dx.doi.org/10.3390/ma15051754
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author González-Sánchez, Manuela
Rivero-Antúnez, Pedro
Cano-Crespo, Rafael
Morales-Flórez, Víctor
author_facet González-Sánchez, Manuela
Rivero-Antúnez, Pedro
Cano-Crespo, Rafael
Morales-Flórez, Víctor
author_sort González-Sánchez, Manuela
collection PubMed
description In this work, a procedure for fabricating porous alumina with the use of a carbon sacrificial template has been tested in order to optimize the fabrication of porous structures mimicking the porosity and mechanical properties of the human cortical bone. Two different sources of sacrificial carbon were used and compared, and different sintering and calcination routes were considered. The porosity of the alumina structures studied by Hg porosimetry revealed that the amount of porosity and the size and shape of the pores are still below the required values, although some acicular pores were clearly observed by SEM. Moreover, measured mechanical properties (Young’s modulus) remained below that of the bone, suggesting the need for further consolidation treatments. In summary, these encouraging results drive the optimization of future fabrication routes.
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spelling pubmed-89110012022-03-11 Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration González-Sánchez, Manuela Rivero-Antúnez, Pedro Cano-Crespo, Rafael Morales-Flórez, Víctor Materials (Basel) Article In this work, a procedure for fabricating porous alumina with the use of a carbon sacrificial template has been tested in order to optimize the fabrication of porous structures mimicking the porosity and mechanical properties of the human cortical bone. Two different sources of sacrificial carbon were used and compared, and different sintering and calcination routes were considered. The porosity of the alumina structures studied by Hg porosimetry revealed that the amount of porosity and the size and shape of the pores are still below the required values, although some acicular pores were clearly observed by SEM. Moreover, measured mechanical properties (Young’s modulus) remained below that of the bone, suggesting the need for further consolidation treatments. In summary, these encouraging results drive the optimization of future fabrication routes. MDPI 2022-02-25 /pmc/articles/PMC8911001/ /pubmed/35268984 http://dx.doi.org/10.3390/ma15051754 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
González-Sánchez, Manuela
Rivero-Antúnez, Pedro
Cano-Crespo, Rafael
Morales-Flórez, Víctor
Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
title Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
title_full Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
title_fullStr Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
title_full_unstemmed Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
title_short Fabrication of Porous Alumina Structures by SPS and Carbon Sacrificial Template for Bone Regeneration
title_sort fabrication of porous alumina structures by sps and carbon sacrificial template for bone regeneration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911001/
https://www.ncbi.nlm.nih.gov/pubmed/35268984
http://dx.doi.org/10.3390/ma15051754
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