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Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients

In recent years, guidelines for the management of acute coronary syndromes (ACS) have placed more emphasis on identifying patients at high bleeding risk (HBR). We set out to investigate the prevalence of HBR patients according to the Academic Research Consortium for High Bleeding Risk (ARC–HBR) crit...

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Autores principales: Kesti, Henri, Mäkinen, Henna, Mattila, Kalle, Jaakkola, Samuli, Lintu, Mikko, Porela, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911016/
https://www.ncbi.nlm.nih.gov/pubmed/35268415
http://dx.doi.org/10.3390/jcm11051324
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author Kesti, Henri
Mäkinen, Henna
Mattila, Kalle
Jaakkola, Samuli
Lintu, Mikko
Porela, Pekka
author_facet Kesti, Henri
Mäkinen, Henna
Mattila, Kalle
Jaakkola, Samuli
Lintu, Mikko
Porela, Pekka
author_sort Kesti, Henri
collection PubMed
description In recent years, guidelines for the management of acute coronary syndromes (ACS) have placed more emphasis on identifying patients at high bleeding risk (HBR). We set out to investigate the prevalence of HBR patients according to the Academic Research Consortium for High Bleeding Risk (ARC–HBR) criteria in hospitalized patients with suspected non-ST-segment elevation myocardial infarction (NSTEMI). Consecutive patients were retrospectively enrolled between January and June 2019 from the emergency department (ED) of a tertiary hospital. The discharge diagnosis and baseline data were manually collected using electronic patient records and database searches. Patients with non-cardiac diagnoses were excluded. Overall, 212 patients were included in the study. A total of 146 (68.9%) patients were diagnosed with NSTEMI (Type 1), 47 (22.2%) with unstable angina pectoris (UAP) and 19 (9.0%) with “other.” HBR was detected in 47.6% (n = 101) of all patients. Common criteria for HBR among ACS patients were age (40.4%), chronic kidney disease (33.7%), and the use of oral anticoagulation medicines (20.2%). In conclusion, nearly half of the patients hospitalized for ACS fulfilled HBR criteria. According to contemporary guidelines, the management of HBR patients differs from that of non-HBR patients, and thus, a more comprehensive screening for HBR may be considered in clinical practice.
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spelling pubmed-89110162022-03-11 Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients Kesti, Henri Mäkinen, Henna Mattila, Kalle Jaakkola, Samuli Lintu, Mikko Porela, Pekka J Clin Med Article In recent years, guidelines for the management of acute coronary syndromes (ACS) have placed more emphasis on identifying patients at high bleeding risk (HBR). We set out to investigate the prevalence of HBR patients according to the Academic Research Consortium for High Bleeding Risk (ARC–HBR) criteria in hospitalized patients with suspected non-ST-segment elevation myocardial infarction (NSTEMI). Consecutive patients were retrospectively enrolled between January and June 2019 from the emergency department (ED) of a tertiary hospital. The discharge diagnosis and baseline data were manually collected using electronic patient records and database searches. Patients with non-cardiac diagnoses were excluded. Overall, 212 patients were included in the study. A total of 146 (68.9%) patients were diagnosed with NSTEMI (Type 1), 47 (22.2%) with unstable angina pectoris (UAP) and 19 (9.0%) with “other.” HBR was detected in 47.6% (n = 101) of all patients. Common criteria for HBR among ACS patients were age (40.4%), chronic kidney disease (33.7%), and the use of oral anticoagulation medicines (20.2%). In conclusion, nearly half of the patients hospitalized for ACS fulfilled HBR criteria. According to contemporary guidelines, the management of HBR patients differs from that of non-HBR patients, and thus, a more comprehensive screening for HBR may be considered in clinical practice. MDPI 2022-02-28 /pmc/articles/PMC8911016/ /pubmed/35268415 http://dx.doi.org/10.3390/jcm11051324 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kesti, Henri
Mäkinen, Henna
Mattila, Kalle
Jaakkola, Samuli
Lintu, Mikko
Porela, Pekka
Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients
title Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients
title_full Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients
title_fullStr Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients
title_full_unstemmed Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients
title_short Prevalence of High Bleeding Risk among Hospitalized Suspected NSTEMI Patients
title_sort prevalence of high bleeding risk among hospitalized suspected nstemi patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911016/
https://www.ncbi.nlm.nih.gov/pubmed/35268415
http://dx.doi.org/10.3390/jcm11051324
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