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Multi-Omics Analysis in β-Thalassemia Using an HBB Gene-Knockout Human Erythroid Progenitor Cell Model

β-thalassemia is a hematologic disease that may be associated with significant morbidity and mortality. Increased expression of HBG1/2 can ameliorate the severity of β-thalassemia. Compared to the unaffected population, some β-thalassemia patients display elevated HBG1/2 expression levels in their r...

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Detalles Bibliográficos
Autores principales: Zhou, Guoqiang, Zhang, Haokun, Lin, Anning, Wu, Zhen, Li, Ting, Zhang, Xumin, Chen, Hongyan, Lu, Daru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911073/
https://www.ncbi.nlm.nih.gov/pubmed/35269949
http://dx.doi.org/10.3390/ijms23052807

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