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The Molecular Basis of FIX Deficiency in Hemophilia B
Coagulation factor IX (FIX) is a vitamin K dependent protein and its deficiency causes hemophilia B, an X-linked recessive bleeding disorder. More than 1000 mutations in the F9 gene have been identified in hemophilia B patients. Here, we systematically summarize the structural and functional charact...
Autores principales: | Shen, Guomin, Gao, Meng, Cao, Qing, Li, Weikai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911121/ https://www.ncbi.nlm.nih.gov/pubmed/35269902 http://dx.doi.org/10.3390/ijms23052762 |
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