Transcriptome Profiling of Osteoblasts in a Medaka (Oryzias latipes) Osteoporosis Model Identifies Mmp13b as Crucial for Osteoclast Activation

Matrix metalloproteases (MMPs) play crucial roles in extracellular matrix (ECM) modulation during osteoclast-driven bone remodeling. In the present study, we used transcriptome profiling of bone cells in a medaka model for osteoporosis and bone regeneration to identify factors critical for bone remo...

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Detalles Bibliográficos
Autores principales: Liu, Ranran, Imangali, Nurgul, Ethiraj, Lalith Prabha, Carney, Tom James, Winkler, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911226/
https://www.ncbi.nlm.nih.gov/pubmed/35281094
http://dx.doi.org/10.3389/fcell.2022.775512

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