Comparative Analysis of Enzymatic Transglycosylation Using E. coli Nucleoside Phosphorylases: A Synthetic Concept for the Preparation of Purine Modified 2′-Deoxyribonucleosides from Ribonucleosides

A comparative analysis of the transglycosylation conditions catalyzed by E. coli nucleoside phosphorylases, leading to the formation of 2′-deoxynucleosides, was performed. We demonstrated that maximal yields of 2′-deoxynucleosides, especially modified, can be achieved under small excess of glycosyl-...

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Detalles Bibliográficos
Autores principales: Drenichev, Mikhail S., Oslovsky, Vladimir E., Zenchenko, Anastasia A., Danilova, Claudia V., Varga, Mikhail A., Esipov, Roman S., Lykoshin, Dmitry D., Alexeev, Cyril S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911250/
https://www.ncbi.nlm.nih.gov/pubmed/35269937
http://dx.doi.org/10.3390/ijms23052795

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