Cargando…

The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women

Ovarian cancer is the fourth-most-common cause of death among all malignant cancers in women in Poland. This study aimed to compare the functioning of the urinary system and quality of life in women in the 12-month period following the completion of surgery or adjuvant treatment for ovarian cancer,...

Descripción completa

Detalles Bibliográficos
Autores principales: Opławski, Marcin, Grabarek, Beniamin Oskar, Średnicka, Agata, Czarniecka, Justyna, Panfil, Agata, Kojs, Zbigniew, Boroń, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911254/
https://www.ncbi.nlm.nih.gov/pubmed/35268391
http://dx.doi.org/10.3390/jcm11051300
_version_ 1784666747637334016
author Opławski, Marcin
Grabarek, Beniamin Oskar
Średnicka, Agata
Czarniecka, Justyna
Panfil, Agata
Kojs, Zbigniew
Boroń, Dariusz
author_facet Opławski, Marcin
Grabarek, Beniamin Oskar
Średnicka, Agata
Czarniecka, Justyna
Panfil, Agata
Kojs, Zbigniew
Boroń, Dariusz
author_sort Opławski, Marcin
collection PubMed
description Ovarian cancer is the fourth-most-common cause of death among all malignant cancers in women in Poland. This study aimed to compare the functioning of the urinary system and quality of life in women in the 12-month period following the completion of surgery or adjuvant treatment for ovarian cancer, with patients who underwent a hysterectomy for non-oncological reasons (control group). The study group consisted of 50 patients diagnosed with stage I–III ovarian cancer. Among 38 patients with type II ovarian cancer (group A), surgery followed by first-line chemotherapy was performed. Within this group of patients, 20 had stage I ovarian cancer, while 18 had stage II ovarian cancer. The study was performed at least 6 months after the final chemotherapy cycle, with no clinical, marker or radiological recurrence determined. On the other hand, in 12 patients with stage I type I ovarian cancer, oncological treatment consisted of only surgery, without the need for adjuvant chemotherapy, due to the low stage of the lesions (group B). In turn, the control group consisted of 50 women who underwent uterine removal for non-oncological reasons (group C). The assessment of quality of life was conducted using the questionnaires: Satisfaction with Life Scale (SWLS); Incontinence Impact Questionnaire, short form (IIQ-7); Urogenital Distress Inventory (UDI-6); and the Sexual Satisfaction Scale for 3, 6, 9, and 12 months after the conclusion of oncological treatment. During the follow-up, a significant reduction in the quality of everyday life and sexual life was noted among patients with ovarian cancer, more pronounced in group B, compared to the control group (p < 0.05). The risk of urinary incontinence is independent of the treatment regimen chosen for ovarian cancer. It is necessary to consider comprehensive psychological care and sexual therapy in patients with ovarian cancer and their families.
format Online
Article
Text
id pubmed-8911254
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-89112542022-03-11 The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women Opławski, Marcin Grabarek, Beniamin Oskar Średnicka, Agata Czarniecka, Justyna Panfil, Agata Kojs, Zbigniew Boroń, Dariusz J Clin Med Article Ovarian cancer is the fourth-most-common cause of death among all malignant cancers in women in Poland. This study aimed to compare the functioning of the urinary system and quality of life in women in the 12-month period following the completion of surgery or adjuvant treatment for ovarian cancer, with patients who underwent a hysterectomy for non-oncological reasons (control group). The study group consisted of 50 patients diagnosed with stage I–III ovarian cancer. Among 38 patients with type II ovarian cancer (group A), surgery followed by first-line chemotherapy was performed. Within this group of patients, 20 had stage I ovarian cancer, while 18 had stage II ovarian cancer. The study was performed at least 6 months after the final chemotherapy cycle, with no clinical, marker or radiological recurrence determined. On the other hand, in 12 patients with stage I type I ovarian cancer, oncological treatment consisted of only surgery, without the need for adjuvant chemotherapy, due to the low stage of the lesions (group B). In turn, the control group consisted of 50 women who underwent uterine removal for non-oncological reasons (group C). The assessment of quality of life was conducted using the questionnaires: Satisfaction with Life Scale (SWLS); Incontinence Impact Questionnaire, short form (IIQ-7); Urogenital Distress Inventory (UDI-6); and the Sexual Satisfaction Scale for 3, 6, 9, and 12 months after the conclusion of oncological treatment. During the follow-up, a significant reduction in the quality of everyday life and sexual life was noted among patients with ovarian cancer, more pronounced in group B, compared to the control group (p < 0.05). The risk of urinary incontinence is independent of the treatment regimen chosen for ovarian cancer. It is necessary to consider comprehensive psychological care and sexual therapy in patients with ovarian cancer and their families. MDPI 2022-02-27 /pmc/articles/PMC8911254/ /pubmed/35268391 http://dx.doi.org/10.3390/jcm11051300 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Opławski, Marcin
Grabarek, Beniamin Oskar
Średnicka, Agata
Czarniecka, Justyna
Panfil, Agata
Kojs, Zbigniew
Boroń, Dariusz
The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women
title The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women
title_full The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women
title_fullStr The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women
title_full_unstemmed The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women
title_short The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women
title_sort impact of surgical treatment with adjuvant chemotherapy for ovarian cancer on disorders in the urinary system and quality of life in women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911254/
https://www.ncbi.nlm.nih.gov/pubmed/35268391
http://dx.doi.org/10.3390/jcm11051300
work_keys_str_mv AT opławskimarcin theimpactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT grabarekbeniaminoskar theimpactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT srednickaagata theimpactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT czarnieckajustyna theimpactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT panfilagata theimpactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT kojszbigniew theimpactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT borondariusz theimpactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT opławskimarcin impactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT grabarekbeniaminoskar impactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT srednickaagata impactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT czarnieckajustyna impactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT panfilagata impactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT kojszbigniew impactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen
AT borondariusz impactofsurgicaltreatmentwithadjuvantchemotherapyforovariancancerondisordersintheurinarysystemandqualityoflifeinwomen