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Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement

Periprocedural atrial fibrillation (AF) is associated with poor prognosis after transcatheter aortic valve replacement (TAVR). We evaluated the impact of long-term sinus rhythm (SR) maintenance on post-TAVR outcomes. We enrolled 278 patients treated with TAVR including 87 patients with periprocedura...

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Autores principales: Choi, Young, Hwang, Byung-Hee, Oh, Gyu-Chul, Kim, Jin Jin, Choo, Eunho, Kim, Min-Chul, Kim, Juhan, Jung, Hae Ok, Youn, Ho-Joong, Chung, Wook-Sung, Chang, Kiyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911407/
https://www.ncbi.nlm.nih.gov/pubmed/35268420
http://dx.doi.org/10.3390/jcm11051330
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author Choi, Young
Hwang, Byung-Hee
Oh, Gyu-Chul
Kim, Jin Jin
Choo, Eunho
Kim, Min-Chul
Kim, Juhan
Jung, Hae Ok
Youn, Ho-Joong
Chung, Wook-Sung
Chang, Kiyuk
author_facet Choi, Young
Hwang, Byung-Hee
Oh, Gyu-Chul
Kim, Jin Jin
Choo, Eunho
Kim, Min-Chul
Kim, Juhan
Jung, Hae Ok
Youn, Ho-Joong
Chung, Wook-Sung
Chang, Kiyuk
author_sort Choi, Young
collection PubMed
description Periprocedural atrial fibrillation (AF) is associated with poor prognosis after transcatheter aortic valve replacement (TAVR). We evaluated the impact of long-term sinus rhythm (SR) maintenance on post-TAVR outcomes. We enrolled 278 patients treated with TAVR including 87 patients with periprocedural AF. Patients with periprocedural AF were classified into the AF-sinus rhythm maintained (AF-SRM) group or the sustained AF group according to long-term cardiac rhythm status after discharge. Patients without AF before or after TAVR were classified into the SR group. The primary clinical outcome was a composite of all-cause death, stroke, or heart failure rehospitalization. The AF-SRM and the SR groups showed significant improvements in left ventricular ejection fraction and left atrial volume index at one year after TAVR, while the sustained AF group did not. During 24.5 (±16.1) months of follow-up, the sustained AF group had a higher risk of the adverse clinical event compared with the AF-SRM group (hazard ratio (HR) 4.449, 95% confidence interval (CI) 1.614–12.270), while the AF-SRM group had a similar risk of the adverse clinical event compared with the SR group (HR 0.737, 95% CI 0.285–1.903). In conclusion, SR maintenance after TAVR was associated with enhanced echocardiographic improvement and favorable clinical outcomes.
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spelling pubmed-89114072022-03-11 Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement Choi, Young Hwang, Byung-Hee Oh, Gyu-Chul Kim, Jin Jin Choo, Eunho Kim, Min-Chul Kim, Juhan Jung, Hae Ok Youn, Ho-Joong Chung, Wook-Sung Chang, Kiyuk J Clin Med Article Periprocedural atrial fibrillation (AF) is associated with poor prognosis after transcatheter aortic valve replacement (TAVR). We evaluated the impact of long-term sinus rhythm (SR) maintenance on post-TAVR outcomes. We enrolled 278 patients treated with TAVR including 87 patients with periprocedural AF. Patients with periprocedural AF were classified into the AF-sinus rhythm maintained (AF-SRM) group or the sustained AF group according to long-term cardiac rhythm status after discharge. Patients without AF before or after TAVR were classified into the SR group. The primary clinical outcome was a composite of all-cause death, stroke, or heart failure rehospitalization. The AF-SRM and the SR groups showed significant improvements in left ventricular ejection fraction and left atrial volume index at one year after TAVR, while the sustained AF group did not. During 24.5 (±16.1) months of follow-up, the sustained AF group had a higher risk of the adverse clinical event compared with the AF-SRM group (hazard ratio (HR) 4.449, 95% confidence interval (CI) 1.614–12.270), while the AF-SRM group had a similar risk of the adverse clinical event compared with the SR group (HR 0.737, 95% CI 0.285–1.903). In conclusion, SR maintenance after TAVR was associated with enhanced echocardiographic improvement and favorable clinical outcomes. MDPI 2022-02-28 /pmc/articles/PMC8911407/ /pubmed/35268420 http://dx.doi.org/10.3390/jcm11051330 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Choi, Young
Hwang, Byung-Hee
Oh, Gyu-Chul
Kim, Jin Jin
Choo, Eunho
Kim, Min-Chul
Kim, Juhan
Jung, Hae Ok
Youn, Ho-Joong
Chung, Wook-Sung
Chang, Kiyuk
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
title Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
title_full Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
title_fullStr Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
title_full_unstemmed Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
title_short Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
title_sort long-term maintenance of sinus rhythm is associated with favorable echocardiographic remodeling and improved clinical outcomes after transcatheter aortic valve replacement
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911407/
https://www.ncbi.nlm.nih.gov/pubmed/35268420
http://dx.doi.org/10.3390/jcm11051330
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