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Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema

The aim of this study was to assess the relationship between the viscoelastic properties of tissues and breast-cancer-related lymphedema (BCRL). After a mastectomy, 46 females were allocated into a lymphedema group (L; n = 15, lymphedema occurred) and a control group (C; n = 31, lack of lymphedema)....

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Autores principales: Naczk, Alicja, Doś, Janusz, Górska-Doś, Magdalena, Sibilski, Robert, Gramza, Piotr, Gajewska, Ewa, Naczk, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911425/
https://www.ncbi.nlm.nih.gov/pubmed/35268385
http://dx.doi.org/10.3390/jcm11051294
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author Naczk, Alicja
Doś, Janusz
Górska-Doś, Magdalena
Sibilski, Robert
Gramza, Piotr
Gajewska, Ewa
Naczk, Mariusz
author_facet Naczk, Alicja
Doś, Janusz
Górska-Doś, Magdalena
Sibilski, Robert
Gramza, Piotr
Gajewska, Ewa
Naczk, Mariusz
author_sort Naczk, Alicja
collection PubMed
description The aim of this study was to assess the relationship between the viscoelastic properties of tissues and breast-cancer-related lymphedema (BCRL). After a mastectomy, 46 females were allocated into a lymphedema group (L; n = 15, lymphedema occurred) and a control group (C; n = 31, lack of lymphedema). Bioimpedance spectroscopy was used to test BCRL. The mechanical properties of the tissues in both upper limbs were tested using myotonometry. In group L, tone, stiffness, relaxation time, and creep measured on the biceps brachii of the impaired limb significantly differed from the results on the unimpaired limb. In group C, the differences were not significant. Moreover, both tone and stiffness were inversely correlated with the level of lymphedema (r = −0.72 and r = −0.88, respectively), and both relaxation and creep were significantly related to the level of lymphedema (r = 0.71 and r = 0.59, respectively), when myotonometry was completed on the biceps brachii of the impaired limb in group L. The relationships were not significant in group C. Measurements of viscoelastic properties can provide useful information concerning lymphedema. Our findings suggest that significant correlations between selected mechanical properties of the tissues and BCRL can be used in BCRL detection and treatment.
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spelling pubmed-89114252022-03-11 Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema Naczk, Alicja Doś, Janusz Górska-Doś, Magdalena Sibilski, Robert Gramza, Piotr Gajewska, Ewa Naczk, Mariusz J Clin Med Article The aim of this study was to assess the relationship between the viscoelastic properties of tissues and breast-cancer-related lymphedema (BCRL). After a mastectomy, 46 females were allocated into a lymphedema group (L; n = 15, lymphedema occurred) and a control group (C; n = 31, lack of lymphedema). Bioimpedance spectroscopy was used to test BCRL. The mechanical properties of the tissues in both upper limbs were tested using myotonometry. In group L, tone, stiffness, relaxation time, and creep measured on the biceps brachii of the impaired limb significantly differed from the results on the unimpaired limb. In group C, the differences were not significant. Moreover, both tone and stiffness were inversely correlated with the level of lymphedema (r = −0.72 and r = −0.88, respectively), and both relaxation and creep were significantly related to the level of lymphedema (r = 0.71 and r = 0.59, respectively), when myotonometry was completed on the biceps brachii of the impaired limb in group L. The relationships were not significant in group C. Measurements of viscoelastic properties can provide useful information concerning lymphedema. Our findings suggest that significant correlations between selected mechanical properties of the tissues and BCRL can be used in BCRL detection and treatment. MDPI 2022-02-26 /pmc/articles/PMC8911425/ /pubmed/35268385 http://dx.doi.org/10.3390/jcm11051294 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Naczk, Alicja
Doś, Janusz
Górska-Doś, Magdalena
Sibilski, Robert
Gramza, Piotr
Gajewska, Ewa
Naczk, Mariusz
Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema
title Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema
title_full Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema
title_fullStr Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema
title_full_unstemmed Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema
title_short Relationship between Viscoelastic Properties of Tissues and Bioimpedance Spectroscopy in Breast-Cancer-Related Lymphedema
title_sort relationship between viscoelastic properties of tissues and bioimpedance spectroscopy in breast-cancer-related lymphedema
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911425/
https://www.ncbi.nlm.nih.gov/pubmed/35268385
http://dx.doi.org/10.3390/jcm11051294
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