Cargando…

Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management

Breast cancer is one of the most common types of cancer among women globally. It is caused by mutations in the estrogen/progesterone receptors and conventional treatment methods are commonly utilized. About 70–80 percent of individuals with the early-stage non-metastatic disease may be cured. Conven...

Descripción completa

Detalles Bibliográficos
Autores principales: Tagde, Priti, Najda, Agnieszka, Nagpal, Kalpana, Kulkarni, Giriraj T., Shah, Muddaser, Ullah, Obaid, Balant, Sebastian, Rahman, Md. Habibur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911433/
https://www.ncbi.nlm.nih.gov/pubmed/35269998
http://dx.doi.org/10.3390/ijms23052856
_version_ 1784666803836813312
author Tagde, Priti
Najda, Agnieszka
Nagpal, Kalpana
Kulkarni, Giriraj T.
Shah, Muddaser
Ullah, Obaid
Balant, Sebastian
Rahman, Md. Habibur
author_facet Tagde, Priti
Najda, Agnieszka
Nagpal, Kalpana
Kulkarni, Giriraj T.
Shah, Muddaser
Ullah, Obaid
Balant, Sebastian
Rahman, Md. Habibur
author_sort Tagde, Priti
collection PubMed
description Breast cancer is one of the most common types of cancer among women globally. It is caused by mutations in the estrogen/progesterone receptors and conventional treatment methods are commonly utilized. About 70–80 percent of individuals with the early-stage non-metastatic disease may be cured. Conventional treatment is far less than the optimal ratio, as demonstrated through the high mortality rate of women with this cancer. However, conventional treatment methods like surgery, radiotherapy, and chemotherapy are not as effective as expected and lead to concerns about low bioavailability, low cellular uptake, emerging resistance, and adverse toxicities. A nanomedicine-based approach is a promising alternative for breast cancer treatment. The present era is witnessing rapid advancements in nanomedicine as a platform for investigating novel therapeutic applications and modern intelligent healthcare management strategies. This paper focuses on nanomedicine-based therapeutic interventions that are becoming more widely accepted for improving treatment effectiveness and reducing undesired side effects in breast cancer patients. By evaluating the state-of-the-art tools and taking the challenges involved into consideration, various aspects of the proposed nano-enabled therapeutic approaches have been discussed in this review.
format Online
Article
Text
id pubmed-8911433
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-89114332022-03-11 Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management Tagde, Priti Najda, Agnieszka Nagpal, Kalpana Kulkarni, Giriraj T. Shah, Muddaser Ullah, Obaid Balant, Sebastian Rahman, Md. Habibur Int J Mol Sci Review Breast cancer is one of the most common types of cancer among women globally. It is caused by mutations in the estrogen/progesterone receptors and conventional treatment methods are commonly utilized. About 70–80 percent of individuals with the early-stage non-metastatic disease may be cured. Conventional treatment is far less than the optimal ratio, as demonstrated through the high mortality rate of women with this cancer. However, conventional treatment methods like surgery, radiotherapy, and chemotherapy are not as effective as expected and lead to concerns about low bioavailability, low cellular uptake, emerging resistance, and adverse toxicities. A nanomedicine-based approach is a promising alternative for breast cancer treatment. The present era is witnessing rapid advancements in nanomedicine as a platform for investigating novel therapeutic applications and modern intelligent healthcare management strategies. This paper focuses on nanomedicine-based therapeutic interventions that are becoming more widely accepted for improving treatment effectiveness and reducing undesired side effects in breast cancer patients. By evaluating the state-of-the-art tools and taking the challenges involved into consideration, various aspects of the proposed nano-enabled therapeutic approaches have been discussed in this review. MDPI 2022-03-05 /pmc/articles/PMC8911433/ /pubmed/35269998 http://dx.doi.org/10.3390/ijms23052856 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tagde, Priti
Najda, Agnieszka
Nagpal, Kalpana
Kulkarni, Giriraj T.
Shah, Muddaser
Ullah, Obaid
Balant, Sebastian
Rahman, Md. Habibur
Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management
title Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management
title_full Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management
title_fullStr Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management
title_full_unstemmed Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management
title_short Nanomedicine-Based Delivery Strategies for Breast Cancer Treatment and Management
title_sort nanomedicine-based delivery strategies for breast cancer treatment and management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911433/
https://www.ncbi.nlm.nih.gov/pubmed/35269998
http://dx.doi.org/10.3390/ijms23052856
work_keys_str_mv AT tagdepriti nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement
AT najdaagnieszka nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement
AT nagpalkalpana nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement
AT kulkarnigirirajt nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement
AT shahmuddaser nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement
AT ullahobaid nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement
AT balantsebastian nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement
AT rahmanmdhabibur nanomedicinebaseddeliverystrategiesforbreastcancertreatmentandmanagement