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Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences

Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the conventional study of protein–host interactions, t...

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Autores principales: Boulahtouf, Zakaria, Virzì, Alessia, Baumert, Thomas F., Verrier, Eloi R., Lupberger, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911453/
https://www.ncbi.nlm.nih.gov/pubmed/35269929
http://dx.doi.org/10.3390/ijms23052787
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author Boulahtouf, Zakaria
Virzì, Alessia
Baumert, Thomas F.
Verrier, Eloi R.
Lupberger, Joachim
author_facet Boulahtouf, Zakaria
Virzì, Alessia
Baumert, Thomas F.
Verrier, Eloi R.
Lupberger, Joachim
author_sort Boulahtouf, Zakaria
collection PubMed
description Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the conventional study of protein–host interactions, the rapid technological development of -omics and bioinformatics has allowed highlighting the important role of signaling networks in viral pathogenesis. In this review, we provide an integrated look on the three major viruses associated with chronic viral hepatitis in patients, summarizing similarities and differences in virus-induced cellular signaling relevant to the viral life cycles and liver disease progression.
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spelling pubmed-89114532022-03-11 Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences Boulahtouf, Zakaria Virzì, Alessia Baumert, Thomas F. Verrier, Eloi R. Lupberger, Joachim Int J Mol Sci Review Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the conventional study of protein–host interactions, the rapid technological development of -omics and bioinformatics has allowed highlighting the important role of signaling networks in viral pathogenesis. In this review, we provide an integrated look on the three major viruses associated with chronic viral hepatitis in patients, summarizing similarities and differences in virus-induced cellular signaling relevant to the viral life cycles and liver disease progression. MDPI 2022-03-03 /pmc/articles/PMC8911453/ /pubmed/35269929 http://dx.doi.org/10.3390/ijms23052787 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Boulahtouf, Zakaria
Virzì, Alessia
Baumert, Thomas F.
Verrier, Eloi R.
Lupberger, Joachim
Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences
title Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences
title_full Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences
title_fullStr Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences
title_full_unstemmed Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences
title_short Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences
title_sort signaling induced by chronic viral hepatitis: dependence and consequences
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911453/
https://www.ncbi.nlm.nih.gov/pubmed/35269929
http://dx.doi.org/10.3390/ijms23052787
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