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Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences
Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the conventional study of protein–host interactions, t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911453/ https://www.ncbi.nlm.nih.gov/pubmed/35269929 http://dx.doi.org/10.3390/ijms23052787 |
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author | Boulahtouf, Zakaria Virzì, Alessia Baumert, Thomas F. Verrier, Eloi R. Lupberger, Joachim |
author_facet | Boulahtouf, Zakaria Virzì, Alessia Baumert, Thomas F. Verrier, Eloi R. Lupberger, Joachim |
author_sort | Boulahtouf, Zakaria |
collection | PubMed |
description | Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the conventional study of protein–host interactions, the rapid technological development of -omics and bioinformatics has allowed highlighting the important role of signaling networks in viral pathogenesis. In this review, we provide an integrated look on the three major viruses associated with chronic viral hepatitis in patients, summarizing similarities and differences in virus-induced cellular signaling relevant to the viral life cycles and liver disease progression. |
format | Online Article Text |
id | pubmed-8911453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89114532022-03-11 Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences Boulahtouf, Zakaria Virzì, Alessia Baumert, Thomas F. Verrier, Eloi R. Lupberger, Joachim Int J Mol Sci Review Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the conventional study of protein–host interactions, the rapid technological development of -omics and bioinformatics has allowed highlighting the important role of signaling networks in viral pathogenesis. In this review, we provide an integrated look on the three major viruses associated with chronic viral hepatitis in patients, summarizing similarities and differences in virus-induced cellular signaling relevant to the viral life cycles and liver disease progression. MDPI 2022-03-03 /pmc/articles/PMC8911453/ /pubmed/35269929 http://dx.doi.org/10.3390/ijms23052787 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Boulahtouf, Zakaria Virzì, Alessia Baumert, Thomas F. Verrier, Eloi R. Lupberger, Joachim Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences |
title | Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences |
title_full | Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences |
title_fullStr | Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences |
title_full_unstemmed | Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences |
title_short | Signaling Induced by Chronic Viral Hepatitis: Dependence and Consequences |
title_sort | signaling induced by chronic viral hepatitis: dependence and consequences |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911453/ https://www.ncbi.nlm.nih.gov/pubmed/35269929 http://dx.doi.org/10.3390/ijms23052787 |
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