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Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management
Paravalvular leak incidence after mitral surgical replacement ranges from 7% to 17%. Between 1% and 5% of these are clinically significant. Large PVLs can cause important clinical manifestations such as heart failure or haemolysis. Current guidelines consider that surgical reparation is the gold-sta...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911516/ https://www.ncbi.nlm.nih.gov/pubmed/35268336 http://dx.doi.org/10.3390/jcm11051245 |
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author | Cruz-Gonzalez, Ignacio Antunez-Muiños, Pablo Lopez-Tejero, Sergio Sanchez, Pedro L. |
author_facet | Cruz-Gonzalez, Ignacio Antunez-Muiños, Pablo Lopez-Tejero, Sergio Sanchez, Pedro L. |
author_sort | Cruz-Gonzalez, Ignacio |
collection | PubMed |
description | Paravalvular leak incidence after mitral surgical replacement ranges from 7% to 17%. Between 1% and 5% of these are clinically significant. Large PVLs can cause important clinical manifestations such as heart failure or haemolysis. Current guidelines consider that surgical reparation is the gold-standard therapy in symptomatic patients with paravalvular leak. However, these recommendations are based in non-randomized observational registries. On the other hand, transcatheter paravalvular leak closure has shown excellent results with a low rate of complications, and nowadays it is considered the first option in selected patients in some experienced centres. In this review, we summarize the clinical manifestations, diagnosis, procedural details, and results of transcatheter mitral PVL closure. |
format | Online Article Text |
id | pubmed-8911516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89115162022-03-11 Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management Cruz-Gonzalez, Ignacio Antunez-Muiños, Pablo Lopez-Tejero, Sergio Sanchez, Pedro L. J Clin Med Review Paravalvular leak incidence after mitral surgical replacement ranges from 7% to 17%. Between 1% and 5% of these are clinically significant. Large PVLs can cause important clinical manifestations such as heart failure or haemolysis. Current guidelines consider that surgical reparation is the gold-standard therapy in symptomatic patients with paravalvular leak. However, these recommendations are based in non-randomized observational registries. On the other hand, transcatheter paravalvular leak closure has shown excellent results with a low rate of complications, and nowadays it is considered the first option in selected patients in some experienced centres. In this review, we summarize the clinical manifestations, diagnosis, procedural details, and results of transcatheter mitral PVL closure. MDPI 2022-02-25 /pmc/articles/PMC8911516/ /pubmed/35268336 http://dx.doi.org/10.3390/jcm11051245 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Cruz-Gonzalez, Ignacio Antunez-Muiños, Pablo Lopez-Tejero, Sergio Sanchez, Pedro L. Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management |
title | Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management |
title_full | Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management |
title_fullStr | Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management |
title_full_unstemmed | Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management |
title_short | Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management |
title_sort | mitral paravalvular leak: clinical implications, diagnosis and management |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911516/ https://www.ncbi.nlm.nih.gov/pubmed/35268336 http://dx.doi.org/10.3390/jcm11051245 |
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