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Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management

Paravalvular leak incidence after mitral surgical replacement ranges from 7% to 17%. Between 1% and 5% of these are clinically significant. Large PVLs can cause important clinical manifestations such as heart failure or haemolysis. Current guidelines consider that surgical reparation is the gold-sta...

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Autores principales: Cruz-Gonzalez, Ignacio, Antunez-Muiños, Pablo, Lopez-Tejero, Sergio, Sanchez, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911516/
https://www.ncbi.nlm.nih.gov/pubmed/35268336
http://dx.doi.org/10.3390/jcm11051245
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author Cruz-Gonzalez, Ignacio
Antunez-Muiños, Pablo
Lopez-Tejero, Sergio
Sanchez, Pedro L.
author_facet Cruz-Gonzalez, Ignacio
Antunez-Muiños, Pablo
Lopez-Tejero, Sergio
Sanchez, Pedro L.
author_sort Cruz-Gonzalez, Ignacio
collection PubMed
description Paravalvular leak incidence after mitral surgical replacement ranges from 7% to 17%. Between 1% and 5% of these are clinically significant. Large PVLs can cause important clinical manifestations such as heart failure or haemolysis. Current guidelines consider that surgical reparation is the gold-standard therapy in symptomatic patients with paravalvular leak. However, these recommendations are based in non-randomized observational registries. On the other hand, transcatheter paravalvular leak closure has shown excellent results with a low rate of complications, and nowadays it is considered the first option in selected patients in some experienced centres. In this review, we summarize the clinical manifestations, diagnosis, procedural details, and results of transcatheter mitral PVL closure.
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spelling pubmed-89115162022-03-11 Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management Cruz-Gonzalez, Ignacio Antunez-Muiños, Pablo Lopez-Tejero, Sergio Sanchez, Pedro L. J Clin Med Review Paravalvular leak incidence after mitral surgical replacement ranges from 7% to 17%. Between 1% and 5% of these are clinically significant. Large PVLs can cause important clinical manifestations such as heart failure or haemolysis. Current guidelines consider that surgical reparation is the gold-standard therapy in symptomatic patients with paravalvular leak. However, these recommendations are based in non-randomized observational registries. On the other hand, transcatheter paravalvular leak closure has shown excellent results with a low rate of complications, and nowadays it is considered the first option in selected patients in some experienced centres. In this review, we summarize the clinical manifestations, diagnosis, procedural details, and results of transcatheter mitral PVL closure. MDPI 2022-02-25 /pmc/articles/PMC8911516/ /pubmed/35268336 http://dx.doi.org/10.3390/jcm11051245 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Cruz-Gonzalez, Ignacio
Antunez-Muiños, Pablo
Lopez-Tejero, Sergio
Sanchez, Pedro L.
Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management
title Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management
title_full Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management
title_fullStr Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management
title_full_unstemmed Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management
title_short Mitral Paravalvular Leak: Clinical Implications, Diagnosis and Management
title_sort mitral paravalvular leak: clinical implications, diagnosis and management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911516/
https://www.ncbi.nlm.nih.gov/pubmed/35268336
http://dx.doi.org/10.3390/jcm11051245
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