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The Effects of Side-Chain Configurations of a Retro–Inverso-Type Inhibitor on the Human T-Cell Leukemia Virus (HTLV)-1 Protease

In this study, the effects of side-chain configurations of D-Ile residues of a retro–inverso (RI)-type inhibitor on the human T-cell leukemia virus type 1 (HTLV-1) protease containing a hydroxyethylamine dipeptide isostere were clarified. Prior to evaluation using the RI-type inhibitor, the effects...

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Detalles Bibliográficos
Autores principales: Awahara, Chiyuki, Oku, Daiki, Furuta, Saki, Kobayashi, Kazuya, Teruya, Kenta, Akaji, Kenichi, Hattori, Yasunao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911550/
https://www.ncbi.nlm.nih.gov/pubmed/35268749
http://dx.doi.org/10.3390/molecules27051646