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Understanding the Biosynthesis of Paxisterol in Lichen-Derived Penicillium aurantiacobrunneum for Production of Fluorinated Derivatives

The U.S. endemic lichen (Niebla homalea)-derived Penicillium aurantiacobrunneum produced a cytotoxic paxisterol derivative named auransterol (2) and epi-citreoviridin (6). Feeding assay using (13)C(1)-labelled sodium acetate not only produced C-13-labelled paxisterol but also confirmed the biosynthe...

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Detalles Bibliográficos
Autores principales: Yamano, Yoshi, Rakotondraibe, Harinantenaina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911623/
https://www.ncbi.nlm.nih.gov/pubmed/35268742
http://dx.doi.org/10.3390/molecules27051641