Completion of the Total Synthesis of Several Bioactive Sarpagine/Macroline Alkaloids including the Important NF-κB Inhibitor N(4)-Methyltalpinine

The unification of the general synthetic strategy regarding the important and emerging group of C-19 methyl-substituted sarpagine/macroline alkaloids has culminated in the completion of the total synthesis of several bioactive alkaloids. Key transformations include an ACE-Cl mediated late-stage N(4)...

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Detalles Bibliográficos
Autores principales: Rahman, Md Toufiqur, Tiruveedhula, Veera Venkata Naga Phani Babu, Stephen, Michael Rajesh, Rallapalli, Sundari K., Pandey, Kamal P., Cook, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911669/
https://www.ncbi.nlm.nih.gov/pubmed/35268836
http://dx.doi.org/10.3390/molecules27051738

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