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Case Report Series: Aggressive HR Deficient Colorectal Cancers Related to BRCA1 Pathogenic Germline Variants

OBJECTIVE: The link between BRCA1 and homologous recombination deficiency (HRD) in cancer has gained importance with the emergence of new targeted cancer treatments, while the available data on the role of the gene in colorectal cancer (CRC) remain contradictory. The aim of this case series was to e...

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Detalles Bibliográficos
Autores principales:	Freire, Maria Valeria, Martin, Marie, Thissen, Romain, Van Marcke, Cédric, Segers, Karin, Sépulchre, Edith, Leroi, Natacha, Lété, Céline, Fasquelle, Corinne, Radermacher, Jean, Gokburun, Yeter, Collignon, Joelle, Sacré, Anne, Josse, Claire, Palmeira, Leonor, Bours, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911702/ https://www.ncbi.nlm.nih.gov/pubmed/35280729 http://dx.doi.org/10.3389/fonc.2022.835581

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