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The Medicinal Natural Products of Cannabis sativa Linn.: A Review

Cannabis sativa is known among many cultures for its medicinal potential. Its complexity contributes to the historical application of various parts of the plant in ethno-medicines and pharmacotherapy. C. sativa has been used for the treatment of rheumatism, epilepsy, asthma, skin burns, pain, the ma...

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Autores principales: Odieka, Anwuli Endurance, Obuzor, Gloria Ukalina, Oyedeji, Opeoluwa Oyehan, Gondwe, Mavuto, Hosu, Yiseyon Sunday, Oyedeji, Adebola Omowunmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911748/
https://www.ncbi.nlm.nih.gov/pubmed/35268790
http://dx.doi.org/10.3390/molecules27051689
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author Odieka, Anwuli Endurance
Obuzor, Gloria Ukalina
Oyedeji, Opeoluwa Oyehan
Gondwe, Mavuto
Hosu, Yiseyon Sunday
Oyedeji, Adebola Omowunmi
author_facet Odieka, Anwuli Endurance
Obuzor, Gloria Ukalina
Oyedeji, Opeoluwa Oyehan
Gondwe, Mavuto
Hosu, Yiseyon Sunday
Oyedeji, Adebola Omowunmi
author_sort Odieka, Anwuli Endurance
collection PubMed
description Cannabis sativa is known among many cultures for its medicinal potential. Its complexity contributes to the historical application of various parts of the plant in ethno-medicines and pharmacotherapy. C. sativa has been used for the treatment of rheumatism, epilepsy, asthma, skin burns, pain, the management of sexually transmitted diseases, difficulties during child labor, postpartum hemorrhage, and gastrointestinal activity. However, the use of C. sativa is still limited, and it is illegal in most countries. Thus, this review aims to highlight the biological potential of the plant parts, as well as the techniques for the extraction, isolation, and characterization of C. sativa compounds. The plant produces a unique class of terpenophenolic compounds, called cannabinoids, as well as non-cannabinoid compounds. The exhaustive profiling of bioactive compounds and the chemical characterization and analysis of C. sativa compounds, which modern research has not yet fully achieved, is needed for the consistency, standardization, and the justified application of Cannabis sativa products for therapeutic purposes. Studies on the clinical relevance and applications of cannabinoids and non-cannabinoid phenols in the prevention and treatment of life-threatening diseases is indeed significant. Furthermore, psychoactive cannabinoids, when chemically standardized and administered under medical supervision, can be the legal answer to the use of C. sativa.
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spelling pubmed-89117482022-03-11 The Medicinal Natural Products of Cannabis sativa Linn.: A Review Odieka, Anwuli Endurance Obuzor, Gloria Ukalina Oyedeji, Opeoluwa Oyehan Gondwe, Mavuto Hosu, Yiseyon Sunday Oyedeji, Adebola Omowunmi Molecules Review Cannabis sativa is known among many cultures for its medicinal potential. Its complexity contributes to the historical application of various parts of the plant in ethno-medicines and pharmacotherapy. C. sativa has been used for the treatment of rheumatism, epilepsy, asthma, skin burns, pain, the management of sexually transmitted diseases, difficulties during child labor, postpartum hemorrhage, and gastrointestinal activity. However, the use of C. sativa is still limited, and it is illegal in most countries. Thus, this review aims to highlight the biological potential of the plant parts, as well as the techniques for the extraction, isolation, and characterization of C. sativa compounds. The plant produces a unique class of terpenophenolic compounds, called cannabinoids, as well as non-cannabinoid compounds. The exhaustive profiling of bioactive compounds and the chemical characterization and analysis of C. sativa compounds, which modern research has not yet fully achieved, is needed for the consistency, standardization, and the justified application of Cannabis sativa products for therapeutic purposes. Studies on the clinical relevance and applications of cannabinoids and non-cannabinoid phenols in the prevention and treatment of life-threatening diseases is indeed significant. Furthermore, psychoactive cannabinoids, when chemically standardized and administered under medical supervision, can be the legal answer to the use of C. sativa. MDPI 2022-03-04 /pmc/articles/PMC8911748/ /pubmed/35268790 http://dx.doi.org/10.3390/molecules27051689 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Odieka, Anwuli Endurance
Obuzor, Gloria Ukalina
Oyedeji, Opeoluwa Oyehan
Gondwe, Mavuto
Hosu, Yiseyon Sunday
Oyedeji, Adebola Omowunmi
The Medicinal Natural Products of Cannabis sativa Linn.: A Review
title The Medicinal Natural Products of Cannabis sativa Linn.: A Review
title_full The Medicinal Natural Products of Cannabis sativa Linn.: A Review
title_fullStr The Medicinal Natural Products of Cannabis sativa Linn.: A Review
title_full_unstemmed The Medicinal Natural Products of Cannabis sativa Linn.: A Review
title_short The Medicinal Natural Products of Cannabis sativa Linn.: A Review
title_sort medicinal natural products of cannabis sativa linn.: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911748/
https://www.ncbi.nlm.nih.gov/pubmed/35268790
http://dx.doi.org/10.3390/molecules27051689
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