Preparation of Thioaminals in Water

The presence of sulfur–carbon bonds is transversal to several areas of chemistry, e.g., drug discovery, materials, and chemical biology. However, a lack of efficient and sustainable procedures for the preparation of thioaminals, the N,S-analogues of O,O-acetals, contributes to this functional group...

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Detalles Bibliográficos
Autores principales: Cavaca, Lídia A. S., Gomes, Rafael F. A., Afonso, Carlos A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911761/
https://www.ncbi.nlm.nih.gov/pubmed/35268774
http://dx.doi.org/10.3390/molecules27051673
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author Cavaca, Lídia A. S.
Gomes, Rafael F. A.
Afonso, Carlos A. M.
author_facet Cavaca, Lídia A. S.
Gomes, Rafael F. A.
Afonso, Carlos A. M.
author_sort Cavaca, Lídia A. S.
collection PubMed
description The presence of sulfur–carbon bonds is transversal to several areas of chemistry, e.g., drug discovery, materials, and chemical biology. However, a lack of efficient and sustainable procedures for the preparation of thioaminals, the N,S-analogues of O,O-acetals, contributes to this functional group often being overlooked by the scientific community. In this work is described the formation of thioaminals in water promoted by copper(II) triflate.
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spelling pubmed-89117612022-03-11 Preparation of Thioaminals in Water Cavaca, Lídia A. S. Gomes, Rafael F. A. Afonso, Carlos A. M. Molecules Article The presence of sulfur–carbon bonds is transversal to several areas of chemistry, e.g., drug discovery, materials, and chemical biology. However, a lack of efficient and sustainable procedures for the preparation of thioaminals, the N,S-analogues of O,O-acetals, contributes to this functional group often being overlooked by the scientific community. In this work is described the formation of thioaminals in water promoted by copper(II) triflate. MDPI 2022-03-03 /pmc/articles/PMC8911761/ /pubmed/35268774 http://dx.doi.org/10.3390/molecules27051673 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cavaca, Lídia A. S.
Gomes, Rafael F. A.
Afonso, Carlos A. M.
Preparation of Thioaminals in Water
title Preparation of Thioaminals in Water
title_full Preparation of Thioaminals in Water
title_fullStr Preparation of Thioaminals in Water
title_full_unstemmed Preparation of Thioaminals in Water
title_short Preparation of Thioaminals in Water
title_sort preparation of thioaminals in water
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911761/
https://www.ncbi.nlm.nih.gov/pubmed/35268774
http://dx.doi.org/10.3390/molecules27051673
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