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Novel Complex of PD-L1 Aptamer and Albumin Enhances Antitumor Efficacy In Vivo
The PD-1/PD-L1 pathway blockade can generate a good clinical response by reducing immunosuppression and provoking durable antitumor immunity. In addition to antibodies, aptamers can also block the interaction between PD-1 and PD-L1. For the in vivo application, however, free aptamers are usually too...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911819/ https://www.ncbi.nlm.nih.gov/pubmed/35268583 http://dx.doi.org/10.3390/molecules27051482 |