Synthesis and Biological Evaluation of 1-(2-(6-Methoxynaphthalen-2-yl)-6-methylnicotinoyl)-4-Substituted Semicarbazides/Thiosemicarbazides as Anti-Tumor Nur77 Modulators

Nur77 is an orphan nuclear receptor that participates in the occurrence and development of a variety of tumors. Many agonists of Nur77 have been reported to have significant anticancer effects. Our previous studies have found that the introduction of bicyclic aromatic rings, such as naphthalyl and q...

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Detalles Bibliográficos
Autores principales: Hu, Hongyu, Huang, Jiangang, Cao, Yin, Zhang, Zhaolin, He, Fengming, Lin, Xianfu, Wu, Qi, Zhao, Shengxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911927/
https://www.ncbi.nlm.nih.gov/pubmed/35268797
http://dx.doi.org/10.3390/molecules27051698

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