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Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders
Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911953/ https://www.ncbi.nlm.nih.gov/pubmed/35268639 http://dx.doi.org/10.3390/molecules27051539 |
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author | Bhatia, Saurabh Makkar, Rashita Behl, Tapan Sehgal, Aayush Singh, Sukhbir Rachamalla, Mahesh Mani, Vasudevan Iqbal, Muhammad Shahid Bungau, Simona Gabriela |
author_facet | Bhatia, Saurabh Makkar, Rashita Behl, Tapan Sehgal, Aayush Singh, Sukhbir Rachamalla, Mahesh Mani, Vasudevan Iqbal, Muhammad Shahid Bungau, Simona Gabriela |
author_sort | Bhatia, Saurabh |
collection | PubMed |
description | Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compounds, as 70 percent of the Earth is covered with oceans, indicating a diversity of chemical entities on the planet. The marine ecosystems are a rich source of bioactive products and have been explored for lead drug molecules that have proven to be novel therapeutic targets. Over the last 70 years, many structurally diverse drug products and their secondary metabolites have been isolated from marine sources. The drugs obtained from marine sources have displayed an exceptional potential in the management of a wide array of diseases, ranging from acute to chronic conditions. A beneficial role of marine drugs in human health has been recently proposed. The current review highlights various marine drugs and their compounds and role in the management of chronic diseases such as cancer, diabetes, neurodegenerative diseases, and cardiovascular disorders, which has led to the development of new drug treatment approaches. |
format | Online Article Text |
id | pubmed-8911953 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89119532022-03-11 Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders Bhatia, Saurabh Makkar, Rashita Behl, Tapan Sehgal, Aayush Singh, Sukhbir Rachamalla, Mahesh Mani, Vasudevan Iqbal, Muhammad Shahid Bungau, Simona Gabriela Molecules Review Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compounds, as 70 percent of the Earth is covered with oceans, indicating a diversity of chemical entities on the planet. The marine ecosystems are a rich source of bioactive products and have been explored for lead drug molecules that have proven to be novel therapeutic targets. Over the last 70 years, many structurally diverse drug products and their secondary metabolites have been isolated from marine sources. The drugs obtained from marine sources have displayed an exceptional potential in the management of a wide array of diseases, ranging from acute to chronic conditions. A beneficial role of marine drugs in human health has been recently proposed. The current review highlights various marine drugs and their compounds and role in the management of chronic diseases such as cancer, diabetes, neurodegenerative diseases, and cardiovascular disorders, which has led to the development of new drug treatment approaches. MDPI 2022-02-24 /pmc/articles/PMC8911953/ /pubmed/35268639 http://dx.doi.org/10.3390/molecules27051539 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bhatia, Saurabh Makkar, Rashita Behl, Tapan Sehgal, Aayush Singh, Sukhbir Rachamalla, Mahesh Mani, Vasudevan Iqbal, Muhammad Shahid Bungau, Simona Gabriela Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders |
title | Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders |
title_full | Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders |
title_fullStr | Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders |
title_full_unstemmed | Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders |
title_short | Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders |
title_sort | biotechnological innovations from ocean: transpiring role of marine drugs in management of chronic disorders |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911953/ https://www.ncbi.nlm.nih.gov/pubmed/35268639 http://dx.doi.org/10.3390/molecules27051539 |
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