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Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders

Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compo...

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Autores principales: Bhatia, Saurabh, Makkar, Rashita, Behl, Tapan, Sehgal, Aayush, Singh, Sukhbir, Rachamalla, Mahesh, Mani, Vasudevan, Iqbal, Muhammad Shahid, Bungau, Simona Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911953/
https://www.ncbi.nlm.nih.gov/pubmed/35268639
http://dx.doi.org/10.3390/molecules27051539
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author Bhatia, Saurabh
Makkar, Rashita
Behl, Tapan
Sehgal, Aayush
Singh, Sukhbir
Rachamalla, Mahesh
Mani, Vasudevan
Iqbal, Muhammad Shahid
Bungau, Simona Gabriela
author_facet Bhatia, Saurabh
Makkar, Rashita
Behl, Tapan
Sehgal, Aayush
Singh, Sukhbir
Rachamalla, Mahesh
Mani, Vasudevan
Iqbal, Muhammad Shahid
Bungau, Simona Gabriela
author_sort Bhatia, Saurabh
collection PubMed
description Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compounds, as 70 percent of the Earth is covered with oceans, indicating a diversity of chemical entities on the planet. The marine ecosystems are a rich source of bioactive products and have been explored for lead drug molecules that have proven to be novel therapeutic targets. Over the last 70 years, many structurally diverse drug products and their secondary metabolites have been isolated from marine sources. The drugs obtained from marine sources have displayed an exceptional potential in the management of a wide array of diseases, ranging from acute to chronic conditions. A beneficial role of marine drugs in human health has been recently proposed. The current review highlights various marine drugs and their compounds and role in the management of chronic diseases such as cancer, diabetes, neurodegenerative diseases, and cardiovascular disorders, which has led to the development of new drug treatment approaches.
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spelling pubmed-89119532022-03-11 Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders Bhatia, Saurabh Makkar, Rashita Behl, Tapan Sehgal, Aayush Singh, Sukhbir Rachamalla, Mahesh Mani, Vasudevan Iqbal, Muhammad Shahid Bungau, Simona Gabriela Molecules Review Marine drugs are abundant in number, comprise of a diverse range of structures with corresponding mechanisms of action, and hold promise for the discovery of new and better treatment approaches for the management of several chronic diseases. There are huge reserves of natural marine biological compounds, as 70 percent of the Earth is covered with oceans, indicating a diversity of chemical entities on the planet. The marine ecosystems are a rich source of bioactive products and have been explored for lead drug molecules that have proven to be novel therapeutic targets. Over the last 70 years, many structurally diverse drug products and their secondary metabolites have been isolated from marine sources. The drugs obtained from marine sources have displayed an exceptional potential in the management of a wide array of diseases, ranging from acute to chronic conditions. A beneficial role of marine drugs in human health has been recently proposed. The current review highlights various marine drugs and their compounds and role in the management of chronic diseases such as cancer, diabetes, neurodegenerative diseases, and cardiovascular disorders, which has led to the development of new drug treatment approaches. MDPI 2022-02-24 /pmc/articles/PMC8911953/ /pubmed/35268639 http://dx.doi.org/10.3390/molecules27051539 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bhatia, Saurabh
Makkar, Rashita
Behl, Tapan
Sehgal, Aayush
Singh, Sukhbir
Rachamalla, Mahesh
Mani, Vasudevan
Iqbal, Muhammad Shahid
Bungau, Simona Gabriela
Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders
title Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders
title_full Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders
title_fullStr Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders
title_full_unstemmed Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders
title_short Biotechnological Innovations from Ocean: Transpiring Role of Marine Drugs in Management of Chronic Disorders
title_sort biotechnological innovations from ocean: transpiring role of marine drugs in management of chronic disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8911953/
https://www.ncbi.nlm.nih.gov/pubmed/35268639
http://dx.doi.org/10.3390/molecules27051539
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