Synthesis of Cyclic N-Acyl Amidines by [3 + 2] Cycloaddition of N-Silyl Enamines and Activated Acyl Azides

In this study, we describe the synthesis of cyclic N-acyl amidines from readily available N-heteroarenes. The synthetic methodology utilized the versatile N-silyl enamine intermediates from the hydrosilylation of N-heteroarenes for the [3 + 2] cycloaddition reaction step. We evaluated various acyl a...

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Detalles Bibliográficos
Autores principales: Jo, Dong Geun, Kim, Changeun, Lee, Sinjae, Yun, Sooyeon, Joung, Seewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912012/
https://www.ncbi.nlm.nih.gov/pubmed/35268798
http://dx.doi.org/10.3390/molecules27051696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912012/
https://www.ncbi.nlm.nih.gov/pubmed/35268798
http://dx.doi.org/10.3390/molecules27051696

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