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Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants
Inositols (Ins) are natural compounds largely widespread in plants and animals. Bio-sinthetically they derive from sugars, possessing a molecular structure very similar to the simple sugars, and this aspect concurs to define them as primary metabolites, even though it is much more correct to place t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912080/ https://www.ncbi.nlm.nih.gov/pubmed/35268625 http://dx.doi.org/10.3390/molecules27051525 |
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author | Siracusa, Laura Napoli, Edoardo Ruberto, Giuseppe |
author_facet | Siracusa, Laura Napoli, Edoardo Ruberto, Giuseppe |
author_sort | Siracusa, Laura |
collection | PubMed |
description | Inositols (Ins) are natural compounds largely widespread in plants and animals. Bio-sinthetically they derive from sugars, possessing a molecular structure very similar to the simple sugars, and this aspect concurs to define them as primary metabolites, even though it is much more correct to place them at the boundary between primary and secondary metabolites. This dichotomy is well represented by the fact that as primary metabolites they are essential cellular components in the form of phospholipid derivatives, while as secondary metabolites they are involved in a plethora of signaling pathways playing an important role in the surviving of living organisms. myo-Inositol is the most important and widespread compound of this family, it derives directly from d-glucose, and all known inositols, including stereoisomers and derivatives, are the results of metabolic processes on this unique molecule. In this review, we report the new insights of these compounds and their derivatives concerning their occurrence in Nature with a particular emphasis on the plant of the Mediterranean area, as well as the new developments about their biological effectiveness. |
format | Online Article Text |
id | pubmed-8912080 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89120802022-03-11 Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants Siracusa, Laura Napoli, Edoardo Ruberto, Giuseppe Molecules Review Inositols (Ins) are natural compounds largely widespread in plants and animals. Bio-sinthetically they derive from sugars, possessing a molecular structure very similar to the simple sugars, and this aspect concurs to define them as primary metabolites, even though it is much more correct to place them at the boundary between primary and secondary metabolites. This dichotomy is well represented by the fact that as primary metabolites they are essential cellular components in the form of phospholipid derivatives, while as secondary metabolites they are involved in a plethora of signaling pathways playing an important role in the surviving of living organisms. myo-Inositol is the most important and widespread compound of this family, it derives directly from d-glucose, and all known inositols, including stereoisomers and derivatives, are the results of metabolic processes on this unique molecule. In this review, we report the new insights of these compounds and their derivatives concerning their occurrence in Nature with a particular emphasis on the plant of the Mediterranean area, as well as the new developments about their biological effectiveness. MDPI 2022-02-24 /pmc/articles/PMC8912080/ /pubmed/35268625 http://dx.doi.org/10.3390/molecules27051525 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Siracusa, Laura Napoli, Edoardo Ruberto, Giuseppe Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants |
title | Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants |
title_full | Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants |
title_fullStr | Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants |
title_full_unstemmed | Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants |
title_short | Novel Chemical and Biological Insights of Inositol Derivatives in Mediterranean Plants |
title_sort | novel chemical and biological insights of inositol derivatives in mediterranean plants |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912080/ https://www.ncbi.nlm.nih.gov/pubmed/35268625 http://dx.doi.org/10.3390/molecules27051525 |
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