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Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes

By combining the excellent biocompatibility of molybdenum disulfide (MoS(2)), excellent surface-enhanced Raman scattering (SERS) activity of Au nanoparticles (Au NPs), and large surface area of Si nanosquare holes (NSHs), a structure in which MoS(2) is decorated with Au NPs on Si NSHs, was proposed...

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Autores principales: Ko, Tsung-Shine, Chen, Yen-Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912446/
https://www.ncbi.nlm.nih.gov/pubmed/35269274
http://dx.doi.org/10.3390/nano12050786
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author Ko, Tsung-Shine
Chen, Yen-Lun
author_facet Ko, Tsung-Shine
Chen, Yen-Lun
author_sort Ko, Tsung-Shine
collection PubMed
description By combining the excellent biocompatibility of molybdenum disulfide (MoS(2)), excellent surface-enhanced Raman scattering (SERS) activity of Au nanoparticles (Au NPs), and large surface area of Si nanosquare holes (NSHs), a structure in which MoS(2) is decorated with Au NPs on Si NSHs, was proposed for SERS applications. The NSH structure fabricated by e-beam lithography possessed 500 nm of squares and a depth of approximately 90 nm. Consequently, a few-layer MoS(2) thin films (2–4 layers) were grown by the sulfurization of the MoO(3) thin film deposited on Si NSHs. SERS measurements indicated that MoS(2) decorated with Au NPs/Si NSHs provided an extremely low limit of detection (ca. 10(−11) M) for R6G, with a high enhancement factor (4.54 × 10(9)) relative to normal Raman spectroscopy. Our results revealed that a large surface area of the NSH structure would probably absorb more R6G molecules and generate more excitons through charge transfer, further leading to the improvement of the chemical mechanism (CM) effect between MoS(2) and R6G. Meanwhile, the electromagnetic mechanism (EM) produced by Au NPs effectively enhances SERS signals. The mechanism of the SERS enhancement in the structure is described and discussed in detail. By combining the hybrid effects of both CM and EM to obtain a highly efficient SERS performance, MoS(2) decorated with Au NPs/Si NSHs is expected to become a new type of SERS substrate for biomedical detection.
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spelling pubmed-89124462022-03-11 Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes Ko, Tsung-Shine Chen, Yen-Lun Nanomaterials (Basel) Article By combining the excellent biocompatibility of molybdenum disulfide (MoS(2)), excellent surface-enhanced Raman scattering (SERS) activity of Au nanoparticles (Au NPs), and large surface area of Si nanosquare holes (NSHs), a structure in which MoS(2) is decorated with Au NPs on Si NSHs, was proposed for SERS applications. The NSH structure fabricated by e-beam lithography possessed 500 nm of squares and a depth of approximately 90 nm. Consequently, a few-layer MoS(2) thin films (2–4 layers) were grown by the sulfurization of the MoO(3) thin film deposited on Si NSHs. SERS measurements indicated that MoS(2) decorated with Au NPs/Si NSHs provided an extremely low limit of detection (ca. 10(−11) M) for R6G, with a high enhancement factor (4.54 × 10(9)) relative to normal Raman spectroscopy. Our results revealed that a large surface area of the NSH structure would probably absorb more R6G molecules and generate more excitons through charge transfer, further leading to the improvement of the chemical mechanism (CM) effect between MoS(2) and R6G. Meanwhile, the electromagnetic mechanism (EM) produced by Au NPs effectively enhances SERS signals. The mechanism of the SERS enhancement in the structure is described and discussed in detail. By combining the hybrid effects of both CM and EM to obtain a highly efficient SERS performance, MoS(2) decorated with Au NPs/Si NSHs is expected to become a new type of SERS substrate for biomedical detection. MDPI 2022-02-25 /pmc/articles/PMC8912446/ /pubmed/35269274 http://dx.doi.org/10.3390/nano12050786 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ko, Tsung-Shine
Chen, Yen-Lun
Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes
title Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes
title_full Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes
title_fullStr Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes
title_full_unstemmed Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes
title_short Hybrid Enhancement of Surface-Enhanced Raman Scattering Using Few-Layer MoS(2) Decorated with Au Nanoparticles on Si Nanosquare Holes
title_sort hybrid enhancement of surface-enhanced raman scattering using few-layer mos(2) decorated with au nanoparticles on si nanosquare holes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912446/
https://www.ncbi.nlm.nih.gov/pubmed/35269274
http://dx.doi.org/10.3390/nano12050786
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