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Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices
Due to the current COVID-19 pandemic, there is a crucial need for the development of antimicrobial and antiviral personal protective equipment such as facemasks and gowns. Therefore, in this research we fabricated electrospun nanofibers composite with polyvinyl alcohol, aloe vera, and zinc oxide nan...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912846/ https://www.ncbi.nlm.nih.gov/pubmed/35267852 http://dx.doi.org/10.3390/polym14051029 |
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author | Munir, Muhammad Usman Mikucioniene, Daiva Khanzada, Haleema Khan, Muhammad Qamar |
author_facet | Munir, Muhammad Usman Mikucioniene, Daiva Khanzada, Haleema Khan, Muhammad Qamar |
author_sort | Munir, Muhammad Usman |
collection | PubMed |
description | Due to the current COVID-19 pandemic, there is a crucial need for the development of antimicrobial and antiviral personal protective equipment such as facemasks and gowns. Therefore, in this research we fabricated electrospun nanofibers composite with polyvinyl alcohol, aloe vera, and zinc oxide nanoparticles for end application in medical devices. Electrospun nanofibers were made with varying concentrations of aloe vera (1%, 2%, 3%, 4%) having a constant concentration of ZnO (0.5%) with varying concentrations of ZnO nanoparticles (1%, 2%, 3%, 4%) having a constant concentration of aloe vera (0.5%). To check the morphology and composition, all prepared nanofibers were subjected to different characterization techniques, such as Scanning Electron Microscopy (SEM), and Fourier Transform Infrared Spectroscopy (FTIR). In addition, its antimicrobial activity was checked both with qualitative and quantitative approaches against gram-positive (Staphylococcus aureus) bacteria and gram-negative (Escherichia coli) bacteria. The results suggest that increasing ZnO concentration kills and inhibits bacterial growth more proficiently compared to increasing aloe vera concentration in electrospun nanofibers; the highest antimicrobial was found with 4% ZnO, killing almost 100% of gram-positive (Staphylococcus aureus) bacteria and 99.2% of gram-negative (Escherichia coli) bacteria. These fabricated nanofibers have potential applications in medical devices and would help control the spread of many diseases. |
format | Online Article Text |
id | pubmed-8912846 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89128462022-03-11 Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices Munir, Muhammad Usman Mikucioniene, Daiva Khanzada, Haleema Khan, Muhammad Qamar Polymers (Basel) Article Due to the current COVID-19 pandemic, there is a crucial need for the development of antimicrobial and antiviral personal protective equipment such as facemasks and gowns. Therefore, in this research we fabricated electrospun nanofibers composite with polyvinyl alcohol, aloe vera, and zinc oxide nanoparticles for end application in medical devices. Electrospun nanofibers were made with varying concentrations of aloe vera (1%, 2%, 3%, 4%) having a constant concentration of ZnO (0.5%) with varying concentrations of ZnO nanoparticles (1%, 2%, 3%, 4%) having a constant concentration of aloe vera (0.5%). To check the morphology and composition, all prepared nanofibers were subjected to different characterization techniques, such as Scanning Electron Microscopy (SEM), and Fourier Transform Infrared Spectroscopy (FTIR). In addition, its antimicrobial activity was checked both with qualitative and quantitative approaches against gram-positive (Staphylococcus aureus) bacteria and gram-negative (Escherichia coli) bacteria. The results suggest that increasing ZnO concentration kills and inhibits bacterial growth more proficiently compared to increasing aloe vera concentration in electrospun nanofibers; the highest antimicrobial was found with 4% ZnO, killing almost 100% of gram-positive (Staphylococcus aureus) bacteria and 99.2% of gram-negative (Escherichia coli) bacteria. These fabricated nanofibers have potential applications in medical devices and would help control the spread of many diseases. MDPI 2022-03-04 /pmc/articles/PMC8912846/ /pubmed/35267852 http://dx.doi.org/10.3390/polym14051029 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Munir, Muhammad Usman Mikucioniene, Daiva Khanzada, Haleema Khan, Muhammad Qamar Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices |
title | Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices |
title_full | Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices |
title_fullStr | Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices |
title_full_unstemmed | Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices |
title_short | Development of Eco-Friendly Nanomembranes of Aloe vera/PVA/ZnO for Potential Applications in Medical Devices |
title_sort | development of eco-friendly nanomembranes of aloe vera/pva/zno for potential applications in medical devices |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912846/ https://www.ncbi.nlm.nih.gov/pubmed/35267852 http://dx.doi.org/10.3390/polym14051029 |
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