Untargeted Metabolome Analysis Reveals Reductions in Maternal Hepatic Glucose and Amino Acid Content That Correlate with Fetal Organ Weights in a Mouse Model of Fetal Alcohol Spectrum Disorders

Prenatal alcohol exposure (PAE) causes fetal growth restrictions. A major driver of fetal growth deficits is maternal metabolic disruption; this is under-investigated following PAE. Untargeted metabolomics on the dam and fetus exposed to alcohol (ALC) revealed that the hepatic metabolome of ALC and...

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Detalles Bibliográficos
Autores principales: Saini, Nipun, Virdee, Manjot S., Helfrich, Kaylee K., Kwan, Sze Ting Cecilia, Mooney, Sandra M., Smith, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912878/
https://www.ncbi.nlm.nih.gov/pubmed/35268071
http://dx.doi.org/10.3390/nu14051096

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