Parallel evolution of Pseudomonas aeruginosa phage resistance and virulence loss in response to phage treatment in vivo and in vitro

With rising antibiotic resistance, there has been increasing interest in treating pathogenic bacteria with bacteriophages (phage therapy). One limitation of phage therapy is the ease at which bacteria can evolve resistance. Negative effects of resistance may be mitigated when resistance results in r...

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Detalles Bibliográficos
Autores principales: Castledine, Meaghan, Padfield, Daniel, Sierocinski, Pawel, Soria Pascual, Jesica, Hughes, Adam, Mäkinen, Lotta, Friman, Ville-Petri, Pirnay, Jean-Paul, Merabishvili, Maya, de Vos, Daniel, Buckling, Angus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912922/
https://www.ncbi.nlm.nih.gov/pubmed/35188102
http://dx.doi.org/10.7554/eLife.73679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912922/
https://www.ncbi.nlm.nih.gov/pubmed/35188102
http://dx.doi.org/10.7554/eLife.73679

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