Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Infectious agents have been implicated in the pathogenesis of SLE. The emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a pro-inflammatory cytokine storm and has been linked...

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Autores principales: Nunes, Ana Luisa, Simoes, Leonor, Figueiredo, Carolina, Carvalho, Ruben, Lima, Jandira, Santos, Rui M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913004/
https://www.ncbi.nlm.nih.gov/pubmed/35317091
http://dx.doi.org/10.14740/jmc3880
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author Nunes, Ana Luisa
Simoes, Leonor
Figueiredo, Carolina
Carvalho, Ruben
Lima, Jandira
Santos, Rui M.
author_facet Nunes, Ana Luisa
Simoes, Leonor
Figueiredo, Carolina
Carvalho, Ruben
Lima, Jandira
Santos, Rui M.
author_sort Nunes, Ana Luisa
collection PubMed
description Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Infectious agents have been implicated in the pathogenesis of SLE. The emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a pro-inflammatory cytokine storm and has been linked to autoimmune phenomena, which can lead to the onset of autoimmune diseases. We report the case of a 70-year-old patient who developed a toxic epidermal necrolysis (TEN)-like subacute cutaneous lupus (SCL) as a severe presentation of SLE, 1 month after SARS-CoV-2 infection. After excluding other causes of SLE, treatment was initiated with a successful outcome.
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spelling pubmed-89130042022-03-21 Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection Nunes, Ana Luisa Simoes, Leonor Figueiredo, Carolina Carvalho, Ruben Lima, Jandira Santos, Rui M. J Med Cases Case Report Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs. Infectious agents have been implicated in the pathogenesis of SLE. The emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a pro-inflammatory cytokine storm and has been linked to autoimmune phenomena, which can lead to the onset of autoimmune diseases. We report the case of a 70-year-old patient who developed a toxic epidermal necrolysis (TEN)-like subacute cutaneous lupus (SCL) as a severe presentation of SLE, 1 month after SARS-CoV-2 infection. After excluding other causes of SLE, treatment was initiated with a successful outcome. Elmer Press 2022-02 2022-02-16 /pmc/articles/PMC8913004/ /pubmed/35317091 http://dx.doi.org/10.14740/jmc3880 Text en Copyright 2022, Nunes et al. https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nunes, Ana Luisa
Simoes, Leonor
Figueiredo, Carolina
Carvalho, Ruben
Lima, Jandira
Santos, Rui M.
Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection
title Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection
title_full Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection
title_fullStr Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection
title_full_unstemmed Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection
title_short Toxic Epidermal Necrolysis-Like Lupus Erythematous Presentation Following SARS-CoV-2 Infection
title_sort toxic epidermal necrolysis-like lupus erythematous presentation following sars-cov-2 infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913004/
https://www.ncbi.nlm.nih.gov/pubmed/35317091
http://dx.doi.org/10.14740/jmc3880
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