Design of a Prospective Study on Pharmacokinetic-Guided Dosing of Prophylactic Factor Replacement in Hemophilia A and B (OPTI-CLOT TARGET Study)

In resource-rich countries, almost all severe hemophilia patients receive prophylactic replacement therapy with factor concentrates to prevent spontaneous bleeding in joints and muscles to decrease the development of arthropathy and risk of long-term disability. Pharmacokinetic (PK)-guided dosing ca...

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Detalles Bibliográficos
Autores principales: Goedhart, Tine M.H.J., Bukkems, Laura H., Coppens, Michiel, Fijnvandraat, Karin J., Schols, Saskia E.M., Schutgens, Roger E.G., Eikenboom, Jeroen, Heubel-Moenen, Floor C.J.I., Ypma, Paula F., Nieuwenhuizen, L., Meijer, K., Leebeek, Frank W. G., Mathôt, Ron A.A., Cnossen, Marjon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913178/
https://www.ncbi.nlm.nih.gov/pubmed/35280975
http://dx.doi.org/10.1055/a-1760-0105

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